TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.

TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.

Item
http://www.wikidata.org/entity/Q33849292
Lower Affinity T Cells are Critical Components and Active Participants of the Immune ResponseProgression of relapsing-remitting demyelinating disease does not require increased TCR affinity or epitope spreadConventional and Regulatory CD4+ T Cells That Share Identical TCRs Are Derived from Common Clones.Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against AutoimmunityLow-affinity CD4+ T cells are major responders in the primary immune responseCutting Edge: Dual TCRα Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation.Evolving Approaches in the Identification of Allograft-reactive T and B Cells in Mice and Humans.Rapid identification and expression of human TCRs in retrogenic mice.Retroviral Transduction of Bone Marrow Progenitor Cells to Generate T-cell Receptor Retrogenic Mice.Ectopic Expression of Self-Antigen Drives Regulatory T Cell Development and Not Deletion of Autoimmune T Cells.Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity.Understanding Autoimmune Diabetes through the Prism of the Tri-Molecular Complex.High self-reactivity drives T-bet and potentiates Treg function in tissue-specific autoimmunity.Central tolerance spares the private high-avidity CD4(+) T-cell repertoire specific for an islet antigen in NOD mice.
P2860

TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.

Item
http://www.wikidata.org/entity/Q33849292
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.
@ast
TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.
@en
type
label
TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.
@ast
TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.
@en
prefLabel
TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.
@ast
TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932