Self-antigen presentation by thymic stromal cells: a subtle division of labor.
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Subcellular localization of the autoimmune regulator protein. characterization of nuclear targeting and transcriptional activation domainThymic selection generates a large T cell pool recognizing a self-peptide in humansIn situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectorsThe Thymic Orchestration Involving Aire, miRNAs, and Cell-Cell Interactions during the Induction of Central ToleranceAutophagy in the regulation of pathogen replication and adaptive immunityHassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymusTSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentationCLIP-derived self peptides bound to MHC class II molecules of medullary thymic epithelial cells differ from those of cortical thymic epithelial cells in their diversity, length, and C-terminal processing.Thymic nurse cells exhibit epithelial progenitor phenotype and create unique extra-cytoplasmic membrane space for thymocyte selectionExpression of HLA class II molecules in humanized NOD.Rag1KO.IL2RgcKO mice is critical for development and function of human T and B cells.Lymphostromal interactions in thymic development and function.Diversity in MHC class II antigen presentation.Development of type 1 diabetes mellitus in nonobese diabetic mice follows changes in thymocyte and peripheral T lymphocyte transcriptional activity.Self-representation in the thymus: an extended view.Thymic gene transfer of myelin oligodendrocyte glycoprotein ameliorates the onset but not the progression of autoimmune demyelination.Positive selection of CD4(+) T cells is induced in vivo by agonist and inhibited by antagonist peptides.Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters.Thymus-blood protein interactions are highly effective in negative selection and regulatory T cell induction.Functional redundancy between thymic CD8α+ and Sirpα+ conventional dendritic cells in presentation of blood-derived lysozyme by MHC class II proteins.Miller's seminal studies on the role of thymus in immunity.Thymic rejuvenation and aging.Coxsackievirus B4 infection of human fetal thymus cellsAutophagy-mediated antigen processing in CD4(+) T cell tolerance and immunity.Lymphatics: at the interface of immunity, tolerance, and tumor metastasis.Role of gonadal hormones in programming developmental changes in thymopoietic efficiency and sexual diergism in thymopoiesis.Thymic epithelial cells: antigen presenting cells that regulate T cell repertoire and tolerance development.Medullary thymic epithelial cells, the indispensable player in central tolerance.Evolving role of tumor antigens for future melanoma therapies.The thymic stromal cell line MTSC4 induced thymocyte apoptosis in a non-MHC-restricted manner.Arp2/3 complex controls T cell homeostasis by maintaining surface TCR levels via regulating TCR+ endosome traffickingTemporal increase in thymocyte negative selection parallels enhanced thymic SIRPα+ DC function.The thymic medulla: a unique microenvironment for intercellular self-antigen transferComposition of the HLA-DR-associated human thymus peptidome.Efficient derivation and concise gene expression profiling of human embryonic stem cell-derived mesenchymal progenitors (EMPs).Update on Aire and thymic negative selection.Knocking out of CD38 accelerates development of a lupus-like disease in lpr mice.Transcription profiling of Prss16 (Tssp) can be used to find additional peptidase genes that are candidates for self-peptide generation in the thymus.Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
P2860
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P2860
Self-antigen presentation by thymic stromal cells: a subtle division of labor.
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Self-antigen presentation by thymic stromal cells: a subtle division of labor.
@ast
Self-antigen presentation by thymic stromal cells: a subtle division of labor.
@en
type
label
Self-antigen presentation by thymic stromal cells: a subtle division of labor.
@ast
Self-antigen presentation by thymic stromal cells: a subtle division of labor.
@en
prefLabel
Self-antigen presentation by thymic stromal cells: a subtle division of labor.
@ast
Self-antigen presentation by thymic stromal cells: a subtle division of labor.
@en
P1476
Self-antigen presentation by thymic stromal cells: a subtle division of labor.
@en
P2093
P304
P356
10.1016/S0952-7915(99)00069-2
P577
2000-04-01T00:00:00Z