Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
about
Expression of the autoimmune regulator gene and its relevance to the mechanisms of central and peripheral toleranceDeaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetesHomeostasis and inflammation in the intestineTranscriptional regulation by AIRE: molecular mechanisms of central toleranceDeletional tolerance mediated by extrathymic Aire-expressing cellsModes of Antigen Presentation by Lymph Node Stromal Cells and Their Immunological ImplicationsThe effects of TLR activation on T-cell development and differentiationContributions of nonhematopoietic cells and mediators to immune responses: implications for immunotoxicologyProlonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasitesPrion uptake in the gut: identification of the first uptake and replication sitesEmerging roles of lymphatic endothelium in regulating adaptive immunity.Fibroblastic reticular cells: organization and regulation of the T lymphocyte life cycleImmunomodulatory Function of the Tumor Suppressor p53 in Host Immune Response and the Tumor MicroenvironmentLymph node fibroblastic reticular cells in health and diseaseModulation of Aire regulates the expression of tissue-restricted antigensAutoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytesExtrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cellsRoles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance inductionTolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment.Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.Lymphatic endothelial cells - key players in regulation of tolerance and immunityLymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation.Strategies and challenges in eliciting immunity to melanoma.Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance.Tolerance to the neuron-specific paraneoplastic HuD antigen.Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cellsMaintenance of peripheral tolerance through controlled tissue homing of antigen-specific T cells in K14-mOVA mice.Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions.Expression of thyrotropin receptor, thyroglobulin, sodium-iodide symporter, and thyroperoxidase by fibrocytes depends on AIRE.Shaping the repertoire of tumor-infiltrating effector and regulatory T cells.Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide.Interplay between Inflammatory Responses and Lymphatic Vessels.Control of central and peripheral tolerance by Aire.Normalization of the lymph node T cell stromal microenvironment in lpr/lpr mice is associated with SU5416-induced reduction in autoantibodies.Unlike Th1, Th17 cells mediate sustained autoimmune inflammation and are highly resistant to restimulation-induced cell deathNonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation.Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity.Clues to immune tolerance: the monogenic autoimmune syndromesDendritic cells control fibroblastic reticular network tension and lymph node expansion.Self-antigen presentation by dendritic cells and lymphoid stroma and its implications for autoimmunity.
P2860
Q21296698-412B2B8F-1C93-4BE3-9FA9-2E78E6F9AF7FQ24323734-8D4A4124-9EFC-4817-892E-8D5DC6B6B690Q24613509-BA14B061-6C30-4BE5-A8AE-C5485DA1ECD5Q24648384-F024F0F2-1A8A-44BC-975F-65C1BE039BFAQ24652952-9DBE7858-F494-4340-81E0-9DAFB3310191Q26781338-76E1AF99-9E8A-424D-AD1D-7DDCC7834017Q27001581-265082A5-BCC2-4AC6-B25A-50CDC81C8F76Q27005695-16326CE1-B9A0-4B97-87BB-33828C912402Q27314913-2F168E41-E13C-4C30-B91A-26299A8D28C5Q27347929-10C61AA0-02AD-4D8F-918C-9AF88E143971Q27686792-B7D15BF5-2988-4947-8363-D7F9AF469F06Q27694402-248F377C-29C4-4589-A980-6A14EC17A0C3Q28071935-54214721-11F5-4017-BDE6-5329279E40B2Q28087190-CA707EB8-7F99-43A4-9AF9-1CD2E5C19F5CQ28509341-03FAFFDF-857F-4EB6-8B40-96E91B3630FCQ28512316-CE892C17-1EB6-42B7-9391-FE5C9A757448Q28593219-9FA6DF3B-5CB3-4711-93B5-248340050004Q30300213-4FC46F1E-782F-4963-87BE-7E729012E225Q30414892-6DE28FC7-5A4D-40CA-AC86-340070707911Q30415907-5B979914-2421-4963-BE8D-BFAFAEFE11C3Q30424567-5817307E-8F12-4386-B7FD-01D89B0BC7D9Q30434547-39049A34-64DB-4817-9BF3-F3B6D1E9681EQ30435893-0A325C2D-5EAF-4510-9ADF-C58F72EB610BQ30579730-629CC9C2-E3E0-415C-ACAD-F0156C2C7754Q33459207-9C1BCD5B-402F-4300-9901-0B24538B7C8FQ33703633-9ECD5AA9-639D-436A-A382-6324A3C27508Q33747003-45BAEC14-9C61-4B5C-B9E7-B7C5DFC8952DQ33794995-AEDC36F5-F73B-44F8-ADFA-A8DEE95BF448Q33837137-EB106335-08FB-4033-86CE-BF3F0E61EDEEQ34003592-9618C85F-FF79-4B79-AB9D-2171018746FFQ34081643-630E1F78-6427-4093-895C-6BBDAE683122Q34105706-F63E5F29-0174-4683-9BA6-8C198237B02AQ34177944-AB7DA908-2588-4B10-8C00-086F5648630AQ34193426-C6F0CE2C-6D25-4CA1-A0D1-BD631B98E2B2Q34217243-57DC55A7-2218-4741-A32C-ADD0FF9569ABQ34245299-FA66054F-CE4E-4B1B-A859-2189A78095DEQ34320316-8D90874B-4CE0-4872-B90F-0F87A20E2F50Q34440616-26EDCEAA-FB14-4878-A292-86692C73F672Q34529256-D3DB8AC9-BE47-4233-8A83-52DA2910A665Q34590424-ACA305E2-EAE2-49DE-9CC2-21F277431287
P2860
Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
description
im Dezember 2006 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в грудні 2006
@uk
name
Peripheral antigen display by ...... l tolerance to intestinal self
@en
Peripheral antigen display by ...... l tolerance to intestinal self
@nl
type
label
Peripheral antigen display by ...... l tolerance to intestinal self
@en
Peripheral antigen display by ...... l tolerance to intestinal self
@nl
prefLabel
Peripheral antigen display by ...... l tolerance to intestinal self
@en
Peripheral antigen display by ...... l tolerance to intestinal self
@nl
P2093
P2860
P356
P1433
P1476
Peripheral antigen display by ...... l tolerance to intestinal self
@en
P2093
Ai-ris Yonekura
Alexander C Cheng
Je-Wook Lee
Jessica E Becker
Joan K Heath
Mathieu Epardaud
Shannon J Turley
P2860
P304
P356
10.1038/NI1427
P407
P577
2006-12-31T00:00:00Z