The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
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Aire and T cell developmentThymic and Postthymic Regulation of Naïve CD4(+) T-Cell Lineage Fates in Humans and Mice ModelsTransplant Tolerance Induction in Newborn Infants: Mechanisms, Advantages, and Potential StrategiesPositive and Negative Regulatory Mechanisms for Fine-Tuning Cellularity and Functions of Medullary Thymic Epithelial CellsThe Contribution of Chemokines and Migration to the Induction of Central Tolerance in the ThymusExosomes in the Thymus: Antigen Transfer and VesiclesThymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance InductionAlternative Antigen Processing for MHC Class I: Multiple Roads Lead to RomeMaturation and migration of murine CD4 single positive thymocytes and thymic emigrantsCCR4 promotes medullary entry and thymocyte-dendritic cell interactions required for central tolerance.Regulation of B lymphocytes and plasma cells by innate immune mechanisms and stromal cells in rheumatoid arthritis.Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central toleranceMorphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epitheliumT Cell Adaptive Immunity Proceeds through Environment-Induced Adaptation from the Exposure of Cryptic Genetic VariationPositive and negative selection of the T cell repertoire: what thymocytes see (and don't see)Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance inductionRegulation of T-cell Tolerance by Lymphatic Endothelial Cells.Lymphatic endothelial cells - key players in regulation of tolerance and immunityRoles of the NF-kappaB pathway in lymphocyte development and function.Cutting edge: Antigen-specific thymocyte feedback regulates homeostatic thymic conventional dendritic cell maturation.Shaping the repertoire of tumor-infiltrating effector and regulatory T cells.The molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytesControl of central and peripheral tolerance by Aire.Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymusEpigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells.Three distinct subsets of thymic epithelial cells in rats and mice defined by novel antibodies.Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development.Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice.The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.Regulatory T cells for tolerance therapy: revisiting the concept.Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition.The Role of Dendritic Cells in Central ToleranceIntercellular Protein Transfer from Thymocytes to Thymic Epithelial CellsAge-Related Disruption of Steady-State Thymic Medulla Provokes Autoimmune Phenotype via Perturbing Negative Selection.Natural Th17 cells are critically regulated by functional medullary thymic microenvironments.RANKL-RANK interaction in immune regulatory systems.Functional redundancy between thymic CD8α+ and Sirpα+ conventional dendritic cells in presentation of blood-derived lysozyme by MHC class II proteins.CCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3(+) T CellsAire deficiency promotes TRP-1-specific immune rejection of melanoma.Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells.
P2860
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P2860
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
@en
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
@nl
type
label
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
@en
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
@nl
prefLabel
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
@en
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
@nl
P2860
P356
P1476
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
@en
P2093
Bruno Kyewski
Christian Koble
P2860
P304
P356
10.1084/JEM.20082449
P407
P577
2009-06-29T00:00:00Z