Restoration of wild-type infectivity to human immunodeficiency virus type 1 strains lacking nef by intravirion reverse transcription.
about
HIV-1 Nef inhibits Protease activity and its absence alters protein content of mature viral particlesEffect of polypurine tract (PPT) mutations on human immunodeficiency virus type 1 replication: a virus with a completely randomized PPT retains low infectivity.Role of human immunodeficiency virus type 1 integrase in uncoating of the viral core.Chimeric human immunodeficiency virus type 1 virions that contain the simian immunodeficiency virus nef gene are cyclosporin A resistant.Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner.Treatment of human immunodeficiency virus type 1 virions depleted of cyclophilin A by natural endogenous reverse transcription restores infectivitySecretion modification region-derived peptide disrupts HIV-1 Nef's interaction with mortalin and blocks virus and Nef exosome release.Hallmarks of HIV-1 pathogenesis are modulated by Nef's Secretion Modification RegionInteraction between Reverse Transcriptase and Integrase Is Required for Reverse Transcription during HIV-1 Replication.Chimeric human immunodeficiency virus type 1 (HIV-1) virions containing HIV-2 or simian immunodeficiency virus Nef are resistant to cyclosporine treatment.The S40 residue in HIV-1 Gag p6 impacts local and distal budding determinants, revealing additional late domain activities.The Nef-infectivity enigma: mechanisms of enhanced lentiviral infection.The activity of Nef on HIV-1 infectivityHIV Type 1 Nef is released from infected cells in CD45(+) microvesicles and is present in the plasma of HIV-infected individuals.Disassembly of human immunodeficiency virus type 1 cores in vitro reveals association of Nef with the subviral ribonucleoprotein complex.Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism.Nef does not affect the efficiency of human immunodeficiency virus type 1 fusion with target cells.Characterization of Nef-CXCR4 interactions important for apoptosis induction.Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.HIV-1 Nef enhances both membrane expression and virion incorporation of Env products. A model for the Nef-dependent increase of HIV-1 infectivity.
P2860
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P2860
Restoration of wild-type infectivity to human immunodeficiency virus type 1 strains lacking nef by intravirion reverse transcription.
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Restoration of wild-type infec ...... avirion reverse transcription.
@ast
Restoration of wild-type infec ...... avirion reverse transcription.
@en
type
label
Restoration of wild-type infec ...... avirion reverse transcription.
@ast
Restoration of wild-type infec ...... avirion reverse transcription.
@en
prefLabel
Restoration of wild-type infec ...... avirion reverse transcription.
@ast
Restoration of wild-type infec ...... avirion reverse transcription.
@en
P2093
P2860
P1433
P1476
Restoration of wild-type infec ...... avirion reverse transcription.
@en
P2093
M D Powell
M Garcia-Barrio
P2860
P304
12081-12087
P356
10.1128/JVI.75.24.12081-12087.2001
P577
2001-12-01T00:00:00Z