NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.
about
α-Synuclein modifies huntingtin aggregation in living cellsBinding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NACPersyn, a member of the synuclein family, influences neurofilament network integrityHighly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.Self-oligomerization and protein aggregation of alpha-synuclein in the presence of Coomassie Brilliant Blue.Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disordersCSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementiaMechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases.Alpha-synuclein in Lewy body disease and Alzheimer's disease.Familial associations of Alzheimer disease and essential tremor with Parkinson disease.Neuropathology of synuclein aggregates.The functions of the amyloid precursor protein gene.Cross-seeding effects of amyloid β-protein and α-synuclein.Understanding Aspects of Aluminum Exposure in Alzheimer's Disease Development.The cellular pathology of Parkinson's disease.α-Synuclein modifies mutant huntingtin aggregation and neurotoxicity in Drosophila.Accumulation of NACP/alpha-synuclein in lewy body disease and multiple system atrophyAggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's diseaseOxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease.Alpha-synuclein tertiary contact dynamics.Distinguishing Lewy body dementias from Alzheimer's disease.Role of synucleins in Alzheimer's disease.Poly(ADP-ribose) polymerase-1 in amyloid beta toxicity and Alzheimer's disease.An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicityEnteric alpha-synuclein expression is increased in Parkinson's disease but not Alzheimer's disease.RNA interference mediated silencing of alpha-synuclein in MN9D cells and its effects on cell viabilityGeneration of Rabbit Monoclonal Antibody to Amyloid-β38 (Aβ38): Increased Plasma Aβ38 Levels in Down Syndrome.Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein.Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates.A beta amyloidogenesis: unique, or variation on a systemic theme?Alpha-synuclein overexpression promotes aggregation of mutant huntingtin.Copper(II)-induced self-oligomerization of alpha-synuclein.Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner.Widespread occurrence of alpha-synuclein/NACP-immunoreactive neuronal inclusions in juvenile and adult-onset Hallervorden-Spatz disease with Lewy bodies.Profiling of hypothalamic and hippocampal gene expression in chronically stressed rats treated with St. John's wort extract (STW 3-VI) and fluoxetine.Generation of reactive oxygen species and activation of NF-kappaB by non-Abeta component of Alzheimer's disease amyloid.Cerebrospinal fluid levels of phosphorylated tau and Aβ1-38/Aβ1-40/Aβ1-42 in Alzheimer's disease with PS1 mutations.Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation.Autophagy and Alzheimer's Disease: From Molecular Mechanisms to Therapeutic Implications.
P2860
Q24298430-B1D32751-1B41-4530-BD32-591476307F3EQ24530132-7F18E53D-E975-4B75-B48C-9FD6B6224C81Q28512814-F7C8F058-B2F3-47E3-ADB3-F345A370B6D0Q31078434-FAFC4EE2-85AE-42A9-BBE5-8778B8BCB7E8Q31895751-B88A2D6B-15AE-49C8-81E5-149FD02E3E88Q32121511-E9436383-820F-4DAD-BF09-A8F2142D4F8DQ33239180-2110D142-E60A-44C0-BD64-CC71FB225EE9Q33366459-E9B7050D-101B-4488-8137-1B01725F88E7Q33750063-ABF83020-3D28-43BE-BFE1-5B489E130609Q33955534-A6C6C48B-B787-4916-848F-AB4FB9E60591Q33957376-587F6324-FA2B-448C-A03A-79244D7A1B9DQ34173160-90D2E3B3-8880-4E62-B35B-504F28F447A6Q34284218-661A293C-3D27-482A-8D43-C1B0A7DC88B7Q34499155-2EFDEFBE-5F3D-4D70-93DA-C229DF69A7F1Q34523836-C45E8429-1C1B-4F0A-B6DC-9A328C5DFC64Q35163459-5359FC69-2AFD-4355-BD2B-2C3FEAB966DCQ35456966-A5CA80EF-8358-4D54-898C-2365AC989BECQ35764504-B4CECC29-608F-4A4B-9DCF-D80CD47DB47EQ35773886-97FBD46B-10EB-42F8-B579-A78A09D4B519Q35797475-A2FE766C-1949-4474-8885-8BBF7E4209B6Q36844186-48B53C53-C724-430B-BE8F-F710207FFAFCQ36998833-B4CB6624-7E71-4DAB-8D8D-D5C12E214BD2Q37306581-B6BF2061-86F1-4552-9553-1D198A053339Q37995047-0AE05425-EC73-4E8A-B157-C52A13FD82B0Q38038981-FFF37FAD-45CC-4E4E-9DF7-010F932CD392Q38398341-01C0D159-AB17-443B-B9A6-76C6BE1AA83CQ39998122-FE8C70EC-EB41-49E0-A3D4-3CBBC2518C33Q40506355-43E8123A-06AC-4E2A-960D-8C3A99CA8331Q40810658-2591982E-2B7F-4491-B1D8-E7B5A7388504Q41256308-6E123472-D285-448F-B560-11DC62EDC3ABQ41651595-19951558-C735-4A68-9DF7-77DE1A3C6391Q41920050-4711EF4B-F267-42BA-938B-839C17CF7034Q42158800-B4B4779F-4651-4515-924B-95063524D934Q42409261-7B5F9A3B-36D5-4D5E-A681-27CF610EE73FQ42479971-E03AB430-B7D8-4180-B66C-6155AE6A3963Q42868931-4EF9017F-1670-4D22-A75A-F9B7D60C52D8Q44068698-9B6E8BFE-FC22-4C20-A6EC-C9F70C609D66Q45903959-F3D70EE8-C8C4-4CFE-8F04-3E94C44F36A7Q48426203-36B23124-4328-4435-B262-2F283F243D6FQ50023771-2A19870D-D025-4239-8349-7D582B50AAFD
P2860
NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
NACP, the precursor protein of ...... stimulates A beta aggregation.
@ast
NACP, the precursor protein of ...... stimulates A beta aggregation.
@en
type
label
NACP, the precursor protein of ...... stimulates A beta aggregation.
@ast
NACP, the precursor protein of ...... stimulates A beta aggregation.
@en
prefLabel
NACP, the precursor protein of ...... stimulates A beta aggregation.
@ast
NACP, the precursor protein of ...... stimulates A beta aggregation.
@en
P2093
P2860
P356
P1476
NACP, the precursor protein of ...... stimulates A beta aggregation.
@en
P2093
P2860
P304
P356
10.1073/PNAS.92.20.9141
P407
P577
1995-09-01T00:00:00Z