NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation. - Wikidata - wikimedia - TriplyDB

NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.

NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.

http://www.wikidata.org/entity/Q33888339

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α-Synuclein modifies huntingtin aggregation in living cells Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC Persyn, a member of the synuclein family, influences neurofilament network integrity Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.Self-oligomerization and protein aggregation of alpha-synuclein in the presence of Coomassie Brilliant Blue.Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders CSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementia Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases.Alpha-synuclein in Lewy body disease and Alzheimer's disease.Familial associations of Alzheimer disease and essential tremor with Parkinson disease.Neuropathology of synuclein aggregates.The functions of the amyloid precursor protein gene.Cross-seeding effects of amyloid β-protein and α-synuclein.Understanding Aspects of Aluminum Exposure in Alzheimer's Disease Development.The cellular pathology of Parkinson's disease.α-Synuclein modifies mutant huntingtin aggregation and neurotoxicity in Drosophila.Accumulation of NACP/alpha-synuclein in lewy body disease and multiple system atrophy Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's disease Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease.Alpha-synuclein tertiary contact dynamics.Distinguishing Lewy body dementias from Alzheimer's disease.Role of synucleins in Alzheimer's disease.Poly(ADP-ribose) polymerase-1 in amyloid beta toxicity and Alzheimer's disease.An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity Enteric alpha-synuclein expression is increased in Parkinson's disease but not Alzheimer's disease.RNA interference mediated silencing of alpha-synuclein in MN9D cells and its effects on cell viability Generation of Rabbit Monoclonal Antibody to Amyloid-β38 (Aβ38): Increased Plasma Aβ38 Levels in Down Syndrome.Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein.Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates.A beta amyloidogenesis: unique, or variation on a systemic theme?Alpha-synuclein overexpression promotes aggregation of mutant huntingtin.Copper(II)-induced self-oligomerization of alpha-synuclein.Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner.Widespread occurrence of alpha-synuclein/NACP-immunoreactive neuronal inclusions in juvenile and adult-onset Hallervorden-Spatz disease with Lewy bodies.Profiling of hypothalamic and hippocampal gene expression in chronically stressed rats treated with St. John's wort extract (STW 3-VI) and fluoxetine.Generation of reactive oxygen species and activation of NF-kappaB by non-Abeta component of Alzheimer's disease amyloid.Cerebrospinal fluid levels of phosphorylated tau and Aβ1-38/Aβ1-40/Aβ1-42 in Alzheimer's disease with PS1 mutations.Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation.Autophagy and Alzheimer's Disease: From Molecular Mechanisms to Therapeutic Implications.

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NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.

http://www.wikidata.org/entity/Q33888339

description

1995 nî lūn-bûn

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1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年论文

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Proceedings of the National Academy of Sciences of the United States of America

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A Iwai

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P2860

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

Amyloid precursor protein is localized in growing neurites of neonatal rat brain.

Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids.

Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid.

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system.

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.

Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation.

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9141-9145

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20

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15631207

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7568089

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Alzheimer's disease

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40940

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