Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents.
about
Effect of 6-thioguanine on the stability of duplex DNAMutS inhibits RecA-mediated strand transfer with methylated DNA substrates.Postreplicative mismatch repair.MiR-221/222 target the DNA methyltransferase MGMT in glioma cellsDose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.Construction and characterization of mismatch-containing circular DNA molecules competent for assessment of nick-directed human mismatch repair in vitro.Differential effects of cisplatin and MNNG on dna mutants of Escherichia coli.Formation, repair, and genotoxic properties of bulky DNA adducts formed from tobacco-specific nitrosamines.Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein.Major differences between tumor and normal human cell fates after exposure to chemotherapeutic monofunctional alkylatorReactive Secondary Sequence Oxidative Pathology Polymer Model and Antioxidant Tests.Carcinogen-specific induction of genetic instability.Characterization of nitrogen mustard formamidopyrimidine adduct formation of bis(2-chloroethyl)ethylamine with calf thymus DNA and a human mammary cancer cell lineDNA Polymerases ImuC and DinB Are Involved in DNA Alkylation Damage Tolerance in Pseudomonas aeruginosa and Pseudomonas putidaHsp27 (HSPB1): a possible surrogate molecular marker for loss of heterozygosity (LOH) of chromosome 1p in oligodendrogliomas but not in astrocytomas.Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents.Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks.Alkylation damage causes MMR-dependent chromosomal instability in vertebrate embryos.The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agentsParticipation of DNA repair in the response to 5-fluorouracil.New (alternative) temozolomide regimens for the treatment of glioma.Free-radical polymer science structural cancer model: a review.Role of aldehydes in the toxic and mutagenic effects of nitrosamines.Proteomic analysis of mismatch repair-mediated alkylating agent-induced DNA damage response.An overview of chemical processes that damage cellular DNA: spontaneous hydrolysis, alkylation, and reactions with radicals.Regional treatment strategies for in-transit melanoma metastasis.Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells.Covalent capture of a human O(6)-alkylguanine alkyltransferase-DNA complex using N(1),O(6)-ethanoxanthosine, a mechanism-based crosslinker.Inhibition of NF- κ B by Dehydroxymethylepoxyquinomicin Suppresses Invasion and Synergistically Potentiates Temozolomide and γ -Radiation Cytotoxicity in Glioblastoma Cells.Rapid DNA double-strand breaks resulting from processing of Cr-DNA cross-links by both MutS dimers.Effect of alternative temozolomide schedules on glioblastoma O(6)-methylguanine-DNA methyltransferase activity and survival.RAD51D protects against MLH1-dependent cytotoxic responses to O(6)-methylguanine.Splice site and Germline variations of the MGMT gene in Esophageal cancer from Kashmir Valley: India.Excision Repair Cross-Complementation Group 1 Enzyme as a Molecular Determinant of Responsiveness to Platinum-Based Chemotherapy for non Small-Cell Lung Cancer.Synthesis and characterization of oligonucleotides containing a nitrogen mustard formamidopyrimidine monoadduct of deoxyguanosine.Ascorbate acts as a highly potent inducer of chromate mutagenesis and clastogenesis: linkage to DNA breaks in G2 phase by mismatch repair.Crosstalk between mismatch repair and base excision repair in human gastric cancer.Successful Second-Line Metronomic Temozolomide in Metastatic Paraganglioma: Case Reports and Review of the Literature.
P2860
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P2860
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents.
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents.
@ast
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents.
@en
type
label
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents.
@ast
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents.
@en
prefLabel
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents.
@ast
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents.
@en
P2093
P1433
P1476
Unmasking a killer: DNA O(6)-methylguanine and the cytotoxicity of methylating agents.
@en
P2093
Aquilina G
O'Driscoll M
P407
P577
2000-04-01T00:00:00Z