Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
about
Endocrine fibroblast growth factors 15/19 and 21: from feast to famineBile acid transporters in health and diseaseBile acids: regulation of synthesisThe bile acid sensor FXR protects against dyslipidemia and aortic plaques development induced by the HIV protease inhibitor ritonavir in miceFarnesoid X receptor: a master regulator of hepatic triglyceride and glucose homeostasisPlasticity and expanding complexity of the hepatic transcription factor network during liver developmentFarnesoid X receptor is essential for normal glucose homeostasisRole of nuclear receptor SHP in metabolism and cancer.Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis.All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.Overexpression of nuclear receptor SHP in adipose tissues affects diet-induced obesity and adaptive thermogenesisDietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner.Transcription factor Nrf2 regulates SHP and lipogenic gene expression in hepatic lipid metabolism.Disruption of an SP2/KLF6 repression complex by SHP is required for farnesoid X receptor-induced endothelial cell migration.Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes.Hepatocyte nuclear factor (HNF) 4α transactivation of cytochrome P450 (Cyp) 2d40 promoter is enhanced during pregnancy in mice.Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partnerAlteration of hepatic nuclear receptor-mediated signaling pathways in hepatitis C virus patients with and without a history of alcohol drinking.Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism.The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice.A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.Zinc-induced Dnmt1 expression involves antagonism between MTF-1 and nuclear receptor SHP.FXR and liver carcinogenesisFXR and PXR: potential therapeutic targets in cholestasis.Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.Crosstalk between xenobiotics metabolism and circadian clock.Interaction of Insulin Resistance and Related Genetic Variants With Triglyceride-Associated Genetic VariantsThe p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP.Bile acid signal-induced phosphorylation of small heterodimer partner by protein kinase Cζ is critical for epigenomic regulation of liver metabolic genesBile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation.The transcription cofactor CRTC1 protects from aberrant hepatic lipid accumulation.Farnesoid X receptor-Acting through bile acids to treat metabolic disorders.Altered expression of small heterodimer partner governs cytochrome P450 (CYP) 2D6 induction during pregnancy in CYP2D6-humanized mice.Bile acid receptors in non-alcoholic fatty liver disease.Targeting orphan nuclear receptor SHP in the treatment of metabolic diseases.Epigenomic regulation of bile acid metabolism: emerging role of transcriptional cofactors.Nuclear receptor small heterodimer partner in apoptosis signaling and liver cancer.Steatosis in the liver.Regulation of anti-atherogenic apolipoprotein M gene expression by the orphan nuclear receptor LRH-1.
P2860
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P2860
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
@ast
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
@en
type
label
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
@ast
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
@en
prefLabel
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
@ast
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
@en
P2093
P2860
P356
P1433
P1476
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
@en
P2093
Andy Greenfield
Konstantinos Boulias
Krister Bamberg
Nitsa Katrakili
Peter Underhill
P2860
P304
P356
10.1038/SJ.EMBOJ.7600728
P407
P577
2005-06-23T00:00:00Z