Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking.
about
β2 adrenergic receptor fluorescent protein fusions traffic to the plasma membrane and retain functionalityAgonist-independent nuclear localization of the Apelin, angiotensin AT1, and bradykinin B2 receptorsRapid internalization and recycling of the human neuropeptide Y Y(1) receptorDetection of receptor ligands by monitoring selective stabilization of a Renilla luciferase-tagged, constitutively active mutant, G-protein-coupled receptorVisualization of a functionally enhanced GFP-tagged galanin R2 receptor in PC12 cells: constitutive and ligand-induced internalizationInternalization of the receptor for advanced glycation end products (RAGE) is required to mediate intracellular responsesKnockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo.Visualization of chemokine receptor activation in transgenic mice reveals peripheral activation of CCR2 receptors in states of neuropathic pain.Internalization and desensitization of a green fluorescent protein-tagged P2Y nucleotide receptor are differently controlled by inhibition of calmodulin-dependent protein kinase II.Caveolin-1 alters the pattern of cytoplasmic Ca2+ oscillations and Ca2+-dependent gene expression by enhancing leukotriene receptor desensitizationInternalization and sequestration of the human prostacyclin receptor.Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3.Impact of cell type and epitope tagging on heterologous expression of G protein-coupled receptor: a systematic study on angiotensin type II receptor.A single lys residue on the first intracellular loop modulates the endoplasmic reticulum export and cell-surface expression of α2A-adrenergic receptorConstitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidusA G protein-coupled receptor (GPCR) in red: live cell imaging of the kappa opioid receptor-tdTomato fusion protein (KOPR-tdT) in neuronal cells.Di-acidic motifs in the membrane-distal C termini modulate the transport of angiotensin II receptors from the endoplasmic reticulum to the cell surface.The Theodore Bücher lecture. Investigating signal transduction with genetically encoded fluorescent probes.Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement.Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor.Regulation of the trafficking and function of G protein-coupled receptors by Rab1 GTPase in cardiomyocytes.Fluorescent knock-in mice to decipher the physiopathological role of G protein-coupled receptors.Real-time endocytosis imaging as a rapid assay of ligand-GPCR binding in single cells.Barcoding of GPCR trafficking and signaling through the various trafficking roadmaps by compartmentalized signaling networks.Topological analysis of the complex formed between neurokinin A and the NK2 tachykinin receptor.Alteration of intracellular histamine H2 receptor cycling precedes antagonist-induced upregulation.Internalization of the human CRF receptor 1 is independent of classical phosphorylation sites and of beta-arrestin 1 recruitment.Dimerization of the human receptors for prostacyclin and thromboxane facilitates thromboxane receptor-mediated cAMP generation.A highly effective dominant negative alpha s construct containing mutations that affect distinct functions inhibits multiple Gs-coupled receptor signaling pathways.Intracellular distribution and late endosomal effects of the ocular albinism type 1 gene product: consequences of disease-causing mutations and implications for melanosome biogenesis.G protein-coupled receptors desensitize and down-regulate epidermal growth factor receptors in renal mesangial cells.Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2.Generation of G protein-coupled receptor antibodies differentially sensitive to conformational states.Identification of novel transplantable GPCR recycling motif for drug discovery.Detection of Ligand-activated G Protein-coupled Receptor Internalization by Confocal Microscopy.Quantitative image cytometry for analyzing intracellular trafficking of G protein-coupled receptors on a chemical-trapping single cell array.Fluorescence ratiometric detection of ligand-induced receptor internalization using extracellular coiled-coil tag-probe labeling.Subcellular localization of the five members of the human steroid 5α-reductase family.
P2860
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P2860
Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking.
description
2000 nî lūn-bûn
@nan
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Using green fluorescent protei ...... localization and trafficking.
@ast
Using green fluorescent protei ...... localization and trafficking.
@en
type
label
Using green fluorescent protei ...... localization and trafficking.
@ast
Using green fluorescent protei ...... localization and trafficking.
@en
prefLabel
Using green fluorescent protei ...... localization and trafficking.
@ast
Using green fluorescent protei ...... localization and trafficking.
@en
P1476
Using green fluorescent protei ...... localization and trafficking.
@en
P2093
P304
P356
10.1016/S0165-6147(00)01477-2
P577
2000-05-01T00:00:00Z