The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
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DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosisThe role of oxidative stress in Parkinson's diseaseRNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathwaysDJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADDMitochondrial localization of DJ-1 leads to enhanced neuroprotectionDJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factorStructural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1 † , ‡Conservation of oxidative protein stabilization in an insect homologue of parkinsonism-associated protein DJ-1Genetics in Parkinson disease: Mendelian versus non-Mendelian inheritanceMetabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinomaDJ-1-dependent regulation of oxidative stress in the retinal pigment epithelium (RPE)DJ-1 knock-down impairs astrocyte mitochondrial function.Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice.Identification of novel proteins affected by rotenone in mitochondria of dopaminergic cellsCopy number variability in Parkinson's disease: assembling the puzzle through a systems biology approachAggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations.Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes.Oxidative neurodegeneration is prevented by UCP0045037, an allosteric modulator for the reduced form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7.Identification of glutathione (GSH)-independent glyoxalase III from Schizosaccharomyces pombe.Identification of DJ-1/PARK-7 as a determinant of stroma-dependent and TNF-alpha-induced apoptosis in MDS using mass spectrometry and phosphopeptide analysis.DJ-1, PINK1, and their effects on mitochondrial pathwaysDJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.Pretreatment with Sodium Phenylbutyrate Alleviates Cerebral Ischemia/Reperfusion Injury by Upregulating DJ-1 Protein.Insulin-like growth factor-I activates extracellularly regulated kinase to regulate the p450 side-chain cleavage insulin-like response element in granulosa cellsDJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.A plant DJ-1 homolog is essential for Arabidopsis thaliana chloroplast development.Rasd1 modulates the coactivator function of NonO in the cyclic AMP pathway.The oxidation states of DJ-1 dictate the cell fate in response to oxidative stress triggered by 4-hpr: autophagy or apoptosis?Tau-mediated nuclear depletion and cytoplasmic accumulation of SFPQ in Alzheimer's and Pick's disease.Transcriptional activation of low-density lipoprotein receptor gene by DJ-1 and effect of DJ-1 on cholesterol homeostasisAge-related changes in the retinal pigment epithelium (RPE).Human DJ-1-specific transcriptional activation of tyrosine hydroxylase geneThe DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffoldMonomer DJ-1 and its N-terminal sequence are necessary for mitochondrial localization of DJ-1 mutants.The genetics of Parkinson disease.Programmed cell death and new discoveries in the genetics of parkinsonism.The role of cysteine oxidation in DJ-1 function and dysfunction.Transcriptional activation of the cholecystokinin gene by DJ-1 through interaction of DJ-1 with RREB1 and the effect of DJ-1 on the cholecystokinin level in mice.DJ1 represses glycolysis and cell proliferation by transcriptionally up-regulating Pink1.CIP2A regulates cancer metabolism and CREB phosphorylation in non-small cell lung cancer.
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P2860
The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@ast
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@en
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@en-gb
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@nl
type
label
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@ast
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@en
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@en-gb
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@nl
prefLabel
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@ast
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@en
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@en-gb
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@nl
P2093
P50
P921
P3181
P356
P1476
The Parkinson's disease-associ ...... cts against neuronal apoptosis
@en
P2093
Bruce A Yankner
Changiz Geula
Christina Y Kim
Haoyong Wang
Irina Woldman
Joshua E Elias
P304
P3181
P356
10.1093/HMG/DDI134
P407
P577
2005-03-24T00:00:00Z