Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions
about
β-Turn mimetic-based stabilizers of protein-protein interactions for the study of the non-canonical roles of leucyl-tRNA synthetase.Discovery libraries targeting the major enzyme classes: the serine hydrolases.Discovery of HIV fusion inhibitors targeting gp41 using a comprehensive α-helix mimetic library.Comprehensive peptidomimetic libraries targeting protein-protein interactions.Extension of the CHARMM General Force Field to sulfonyl-containing compounds and its utility in biomolecular simulations.Inhibition of adenovirus replication by a trisubstituted piperazin-2-one derivative.Discovery and Structure-Activity Relationships of the Neoseptins: A New Class of Toll-like Receptor-4 (TLR4) Agonists.Development of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41Diversity of Secondary Structure in Catalytic Peptides with β-Turn-Biased SequencesStructure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.Peptidomimetic therapeutics: scientific approaches and opportunities.Ligand-Enabled γ-C(sp(3))-H Olefination of Amines: En Route to PyrrolidinesEnantioselective organo-SOMO cycloadditions: a catalytic approach to complex pyrrolidines from olefins and aldehydes.In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers.Ester vs. amide on folding: a case study with a 2-residue synthetic peptide.Design, synthesis, and conformational analysis of 3-cyclo-butylcarbamoyl hydantoins as novel hydrogen bond driven universal peptidomimetics.Limiting Assumptions in the Design of Peptidomimetics.Cyclopropane-Based Peptidomimetics Mimicking Wide-Ranging Secondary Structures of Peptides: Conformational Analysis and Their Use in Rational Ligand Optimization.Stereoselective Ag-Catalyzed 1,3-Dipolar Cycloaddition of Activated Trifluoromethyl-Substituted Azomethine Ylides.From Peptides to Peptidomimetics: A Strategy Based on the Structural Features of Cyclopropane.Squaramide-catalysed asymmetric cascade aza-Michael/Michael addition reaction for the synthesis of chiral trisubstituted pyrrolidines.Synthesis and analysis of the conformational preferences of 5-aminomethyloxazolidine-2,4-dione scaffolds: first examples of β(2)- and β(2, 2)-homo-Freidinger lactam analogues
P2860
Q33814121-BF470E93-BB49-44CF-9513-1C9A719AF572Q34036280-49200DB2-A013-40C0-AC47-D7CCF3BEE9F5Q34198487-6A78BF68-DC82-4785-AA2B-36D22DC9C9DDQ34338569-25BC0234-211E-44BF-952A-451CBB3FC98AQ34347574-46C11EDF-C1EE-47C0-B94A-604EF3865B1DQ35183338-C0201A1C-75E1-4BA8-BDB9-83AAE661053FQ35981265-71E2E152-D5AB-41EC-B233-1F8C6892A1E0Q36643050-6F3A1A89-A82C-41E6-AB06-9DC3D41C3144Q37646524-C5CFC42D-74D9-49F9-A55E-C8AF7BA05308Q38539666-436CF35D-1556-499E-82CA-A5F27AC82D1AQ39011193-CA2FB1E2-3A59-45C0-BE0D-9A3298C6B974Q39780805-99CA4019-CA77-4E9F-BE7A-569FEF781606Q41918769-5B6EF0AF-A1C8-4F70-8C29-06EBF226E625Q43653348-2E3D9AC7-3EAB-4A7D-BB95-215B15326B12Q45329378-80D18D1F-B82B-4D7D-8399-8B6A0ADB7EC7Q47279360-597A50E5-EB9F-4328-9209-6E8A6A6B25C3Q47850453-F4F87CB4-0134-44DF-B17B-A18148DC1733Q48130657-284AF1A4-2F66-444C-AC4F-6741E96F6965Q48234168-8090CD9E-3AAB-490E-B6AA-1B249882DD8CQ48250705-A541B131-4BBE-460B-B6A7-F0B5003D51A0Q51700868-63712DA5-7462-40E9-83FA-F401954E4EE2Q56972517-0FA1D75A-19D7-45C1-B11E-FAB75A5D4174
P2860
Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Design, synthesis, and validat ...... peptide-receptor interactions
@ast
Design, synthesis, and validat ...... peptide-receptor interactions
@en
type
label
Design, synthesis, and validat ...... peptide-receptor interactions
@ast
Design, synthesis, and validat ...... peptide-receptor interactions
@en
prefLabel
Design, synthesis, and validat ...... peptide-receptor interactions
@ast
Design, synthesis, and validat ...... peptide-receptor interactions
@en
P2093
P2860
P356
P1476
Design, synthesis, and validat ...... peptide-receptor interactions
@en
P2093
Bryan L Roth
Dale L Boger
Landon R Whitby
Vincent Setola
Yoshio Ando
P2860
P304
10184-10194
P356
10.1021/JA201878V
P407
P50
P577
2011-06-15T00:00:00Z