The motor and tail regions of myosin XV are critical for normal structure and function of auditory and vestibular hair cells.
about
Mutations of human NARS2, encoding the mitochondrial asparaginyl-tRNA synthetase, cause nonsyndromic deafness and Leigh syndromeAutosomal recessive nonsyndromic deafness genes: a reviewMechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.Dynamic length regulation of sensory stereociliaDefects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndromeAn actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewalWhere hearing starts: the development of the mammalian cochleaThe Stereociliary Paracrystal Is a Dynamic Cytoskeletal Scaffold In VivoMutant analysis reveals whirlin as a dynamic organizer in the growing hair cell stereociliumMyosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransductionElongation of hair cell stereocilia is defective in the mouse mutant whirlerMyosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereociliaActin in hair cells and hearing loss.Age-related changes in cochlear gene expression in normal and shaker 2 miceMyosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle.The role of bone morphogenetic protein 4 in inner ear development and function.Myosin VI and VIIa distribution among inner ear epithelia in diverse fishes.Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndromeGenetic spectrum of autosomal recessive non-syndromic hearing loss in Pakistani families.Possible involvement of myosin-X in intercellular adhesion: importance of serial pleckstrin homology regions for intracellular localization.The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearingDisruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear.Genetic Linkage Analysis of 15 DFNB Loci in a Group of Iranian Families with Autosomal Recessive Hearing Loss.Prioritized sequencing of the second exon of MYO15A reveals a new mutation segregating in a Pakistani family with moderate to severe hearing lossWhirler mutant hair cells have less severe pathology than shaker 2 or double mutants.Competition and compensation: dissecting the biophysical and functional differences between the class 3 myosin paralogs, myosins 3a and 3b.Screening of DFNB3 in Iranian families with autosomal recessive non-syndromic hearing loss reveals a novel pathogenic mutation in the MyTh4 domain of the MYO15A gene in a linked familyAuditory and vestibular hair cell stereocilia: relationship between functionality and inner ear disease.Mutational Spectrum of MYO15A and the Molecular Mechanisms of DFNB3 Human Deafness.MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions.Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV.Whole-exome sequencing to identify the cause of congenital sensorineural hearing loss in carriers of a heterozygous GJB2 mutation.Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice.Myosins: Domain Organisation, Motor Properties, Physiological Roles and Cellular Functions.
P2860
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P2860
The motor and tail regions of myosin XV are critical for normal structure and function of auditory and vestibular hair cells.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The motor and tail regions of ...... ory and vestibular hair cells.
@ast
The motor and tail regions of ...... ory and vestibular hair cells.
@en
type
label
The motor and tail regions of ...... ory and vestibular hair cells.
@ast
The motor and tail regions of ...... ory and vestibular hair cells.
@en
prefLabel
The motor and tail regions of ...... ory and vestibular hair cells.
@ast
The motor and tail regions of ...... ory and vestibular hair cells.
@en
P2093
P356
P1476
The motor and tail regions of ...... ory and vestibular hair cells.
@en
P2093
Anderson DW
Belyantseva IA
Fridell RA
Friedman TB
P304
P356
10.1093/HMG/9.12.1729
P577
2000-07-01T00:00:00Z