Identification and characterization of the human ORC6 homolog.
about
ATP-dependent assembly of the human origin recognition complexMaking sense of eukaryotic DNA replication origins.Identification of a binding region for human origin recognition complex proteins 1 and 2 that coincides with an origin of DNA replicationStability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycleAn essential role for Orc6 in DNA replication through maintenance of pre-replicative complexesA approximately 35 kDa polypeptide from insect cells binds to yeast ACS like elements in the presence of ATPThe genes encoding Arabidopsis ORC subunits are E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cellsStructural analysis of human Orc6 protein reveals a homology with transcription factor TFIIBAssembly of the human origin recognition complexArchitecture of the human origin recognition complexNuclear organization of DNA replication initiation proteins in mammalian cellsDifferential analysis of gene regulation at transcript resolution with RNA-seqAcute reduction of an origin recognition complex (ORC) subunit in human cells reveals a requirement of ORC for Cdk2 activation.Recruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cellsA cytokinetic function of Drosophila ORC6 protein resides in a domain distinct from its replication activity.The dyad symmetry element of Epstein-Barr virus is a dominant but dispensable replication origin.Multiple mechanisms regulate subcellular localization of human CDC6.Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus.Identification of ORC1/CDC6-interacting factors in Trypanosoma brucei reveals critical features of origin recognition complex architecture.The ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle.A structural role for ATP in the formation and stability of the human origin recognition complexA vertebrate N-end rule degron reveals that Orc6 is required in mitosis for daughter cell abscissionPolo-like kinase 1 (Plk1): an Unexpected Player in DNA Replication.Diverged composition and regulation of the Trypanosoma brucei origin recognition complex that mediates DNA replication initiationThe origin recognition complex: a biochemical and structural view.The origin recognition complex protein family.A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formationFunctional analysis of an Orc6 mutant in Drosophila.Regulating DNA replication in eukarya.Mechanisms and regulation of DNA replication initiation in eukaryotes.Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1.Differential use of multiple replication origins in the ribosomal DNA episome of the protozoan parasite Entamoeba histolyticaProliferating human cells hypomorphic for origin recognition complex 2 and pre-replicative complex formation have a defect in p53 activation and Cdk2 kinase activation.Identification and characterization of the DNA replication origin recognition complex gene family in the silkworm Bombyx mori.Role of the Orc6 protein in origin recognition complex-dependent DNA binding and replication in Drosophila melanogaster.Trypanosoma brucei Orc1 is essential for nuclear DNA replication and affects both VSG silencing and VSG switching.A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events.Further insight into the phenotype associated with a mutation in the ORC6 gene, causing Meier-Gorlin syndrome 3.Different roles of the human Orc6 protein in the replication initiation process
P2860
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P2860
Identification and characterization of the human ORC6 homolog.
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Identification and characterization of the human ORC6 homolog.
@ast
Identification and characterization of the human ORC6 homolog.
@en
type
label
Identification and characterization of the human ORC6 homolog.
@ast
Identification and characterization of the human ORC6 homolog.
@en
prefLabel
Identification and characterization of the human ORC6 homolog.
@ast
Identification and characterization of the human ORC6 homolog.
@en
P2860
P356
P1476
Identification and characterization of the human ORC6 homolog.
@en
P2860
P304
34983-34988
P356
10.1074/JBC.M006069200
P407
P577
2000-11-01T00:00:00Z