Physical modulation of intracellular signaling processes by locational regulation.
about
Modeling the signaling endosome hypothesis: why a drive to the nucleus is better than a (random) walk.Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular locationSpatial sensing in fibroblasts mediated by 3' phosphoinositides.A bipolar clamp mechanism for activation of Jak-family protein tyrosine kinasesQuantitative understanding of cell signaling: the importance of membrane organization.Computational approaches for modeling regulatory cellular networks.Cell-signalling dynamics in time and space.The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins.Reactions on cell membranes: comparison of continuum theory and Brownian dynamics simulations.Chemotaxis: signalling modules join hands at front and tail.The membrane environment can promote or suppress bistability in cell signaling networks.Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops.Signal transduction at point-blank range: analysis of a spatial coupling mechanism for pathway crosstalkMolecular mechanisms in signal transduction at the membrane.Kinetic proofreading of ligand-FcepsilonRI interactions may persist beyond LAT phosphorylation.Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitorMolecular dynamics simulations reveal that Tyr-317 phosphorylation reduces Shc binding affinity for phosphotyrosyl residues of epidermal growth factor receptorA diffusion-translocation model for gradient sensing by chemotactic cells.A unified model for signal transduction reactions in cellular membranes.Diffusion control of protein phosphorylation in signal transduction pathways.Lck, Membrane Microdomains, and TCR Triggering Machinery: Defining the New Rules of EngagementQuantitative model of Ras-phosphoinositide 3-kinase signalling cross-talk based on co-operative molecular assembly.Endosomal receptor kinetics determine the stability of intracellular growth factor signalling complexes.Independence of protein kinase C-delta activity from activation loop phosphorylation: structural basis and altered functions in cells.Controlling protein activity by dynamic recruitment on a supramolecular polymer platform.Confinement and diffusion modulate bistability and stochastic switching in a reaction network with positive feedback.Cytosolic proteins can exploit membrane localization to trigger functional assembly.A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model.
P2860
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P2860
Physical modulation of intracellular signaling processes by locational regulation.
description
1997 nî lūn-bûn
@nan
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Physical modulation of intracellular signaling processes by locational regulation.
@ast
Physical modulation of intracellular signaling processes by locational regulation.
@en
type
label
Physical modulation of intracellular signaling processes by locational regulation.
@ast
Physical modulation of intracellular signaling processes by locational regulation.
@en
prefLabel
Physical modulation of intracellular signaling processes by locational regulation.
@ast
Physical modulation of intracellular signaling processes by locational regulation.
@en
P2860
P1433
P1476
Physical modulation of intracellular signaling processes by locational regulation.
@en
P2093
Lauffenburger DA
P2860
P304
P356
10.1016/S0006-3495(97)78846-5
P407
P577
1997-05-01T00:00:00Z