Gene therapy for the hemoglobin disorders: past, present, and future. - Wikidata - wikimedia - TriplyDB

Gene therapy for the hemoglobin disorders: past, present, and future.

Gene therapy for the hemoglobin disorders: past, present, and future.

http://www.wikidata.org/entity/Q33915535

about

Transient in vivo beta-globin production after lentiviral gene transfer to hematopoietic stem cells in the nonhuman primate The beta-globin locus control region versus gene therapy vectors: a struggle for expression.Genomic editing tools to model human diseases with isogenic pluripotent stem cells.Globin gene transfer for the treatment of severe hemoglobinopathies: a paradigm for stem cell-based gene therapy.Loss of T cell-mediated antitumor immunity after construct-specific downregulation of retrovirally encoded T-cell receptor expression in vivo.Therapeutic challenges in childhood sickle cell disease. Part 1: current and future treatment options.Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells B-cell-specific transgene expression using a self-inactivating retroviral vector with human CD19 promoter and viral post-transcriptional regulatory element.

P2860

Q33688435-38DC0D3B-457D-4D0C-AA7A-BDD18E643A0B Q34135439-357452B4-3FE1-4CE3-9C7C-1590F37078FF Q34437293-7AEF1B0A-2588-4276-A758-22824CA41E4A Q34587615-55EBCCCB-6BE6-46D5-8341-A7954DD6B71C Q34727843-FF155528-D988-40E0-86B6-8B58C124639A Q35076604-F8FBBFA7-FFDD-4F55-88FD-E0E683F15C5A Q37209028-6596A469-B3F6-4461-A0AD-AAA8D923BD3E Q44296349-7161D264-7218-40DF-80CF-810DBC635E6D

P2860

Gene therapy for the hemoglobin disorders: past, present, and future.

http://www.wikidata.org/entity/Q33915535

description

2000 nî lūn-bûn

@nan

2000 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Gene therapy for the hemoglobin disorders: past, present, and future.

@ast

Gene therapy for the hemoglobin disorders: past, present, and future.

@en

type

label

Gene therapy for the hemoglobin disorders: past, present, and future.

@ast

Gene therapy for the hemoglobin disorders: past, present, and future.

@en

prefLabel

Gene therapy for the hemoglobin disorders: past, present, and future.

@ast

Gene therapy for the hemoglobin disorders: past, present, and future.

@en

P1433

Q33915535-77670FD2-0907-44CE-BC15-AC8D365DB579

P1476

Q33915535-0005FF1B-E533-41C6-86D2-4436DFD2C41A

P2093

Q33915535-D7A43C13-7FE2-4ECF-9B59-2C0B3AF4517C

Q33915535-F84DFA43-EEB0-402B-8205-52C6AD59A243

P2860

Q33915535-02476655-2220-4EEB-8C28-65125C7B6EBC

Q33915535-0D737ADE-3191-456A-B121-F932E94F854D

Q33915535-11B7D497-ADCD-4A7E-9BCF-3C429E910D56

Q33915535-1ACB6D9B-6206-49DF-94E9-BBC9D3D32D8E

Q33915535-2193A7AF-D47F-4F05-8DB0-0EDF71D6914D

Q33915535-26F9AD5F-98FF-4221-9C19-6B960CC422AE

Q33915535-32E77941-48DC-4818-B79F-90E63A0A250D

Q33915535-39971C5B-FFB1-4E37-8499-C8E025D3450B

Q33915535-3DB8F881-1AD8-45A7-A05B-351D531B8300

Q33915535-44F51284-53E5-45B8-82C1-5F86183742FF

P304

Q33915535-5A1746BC-AA08-4D59-85D3-3EBF6A86DBBC

P31

Q33915535-125A1D20-91D9-4476-9F77-F35FA99B01A7

P356

Q33915535-0183D6C9-77AA-4567-A4AF-958A8F87926D

P407

Q33915535-87CFDC97-06E5-42BB-8DE6-C6E0EBEE06D0

P433

Q33915535-1376C728-2F07-46FC-A1FB-8E0C2AF7EE77

P478

Q33915535-0AE25CA2-751C-4939-942C-3D65B3AE8A08

P577

Q33915535-701455D8-26FD-4420-A13D-DAC445313FD9

P5875

Q33915535-E61BA440-E71C-42AD-8ED2-56834A1C1C28

P698

Q33915535-58B96574-7518-4696-B621-E3380E0A4BCF

P921

Q33915535-17D27FD1-F9FC-43F4-9880-859B531A6B05

P932

Q33915535-1C8D93AC-D99A-4271-81FE-ADE6321A0A66

P356

PNAS.97.10.5022

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Gene therapy for the hemoglobin disorders: past, present, and future.

@en

P2093

Nienhuis AW

http://www.w3.org/2001/XMLSchema#string

Persons DA

http://www.w3.org/2001/XMLSchema#string

P2860

Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

Expression of the human beta-globin gene following retroviral-mediated transfer into multipotential hematopoietic progenitors of mice.

Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells.

Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells

Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene.

The human beta-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice.

Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells.

A proliferation switch for genetically modified cells.

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

P304

5022-5024

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.97.10.5022

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

97

http://www.w3.org/2001/XMLSchema#string

P577

2000-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

12511579

http://www.w3.org/2001/XMLSchema#string

P698

10805762

http://www.w3.org/2001/XMLSchema#string

P921

P932

33980

http://www.w3.org/2001/XMLSchema#string