Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype - Wikidata - wikimedia - TriplyDB

Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype

Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype

http://www.wikidata.org/entity/Q33916126

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In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies Biomarkers for glioma immunotherapy: the next generation Developmental origins of brain tumors CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells A secreted PTEN phosphatase that enters cells to alter signaling and survival Cell of origin for malignant gliomas and its implication in therapeutic development Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis.Contribution of tumor heterogeneity in a new animal model of CNS tumors.Lentiviral-induced high-grade gliomas in rats: the effects of PDGFB, HRAS-G12V, AKT, and IDH1-R132H.Ribosome profiling reveals a cell-type-specific translational landscape in brain tumors.Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma.MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma.Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas.The cellular origin for malignant glioma and prospects for clinical advancements.ASYMMETRIC CELL DIVISION: IMPLICATIONS FOR GLIOMA DEVELOPMENT AND TREATMENT.Glial progenitors as targets for transformation in glioma.A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors.Signal transducer and activator of transcription 5b drives malignant progression in a PDGFB-dependent proneural glioma model by suppressing apoptosis.Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation.The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma.Capturing the molecular and biological diversity of high-grade astrocytoma in genetically engineered mouse models Review: insights gained from modelling high-grade glioma in the mouse.Glial progenitor cell recruitment drives aggressive glioma growth: mathematical and experimental modelling.Identification of global alteration of translational regulation in glioma in vivo PDGF-B-mediated downregulation of miR-21: new insights into PDGF signaling in glioblastoma.Cell of origin determines clinically relevant subtypes of MLL-rearranged AML Candidate pathways for promoting differentiation or quiescence of oligodendrocyte progenitor-like cells in glioma.MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma Intricate interplay between astrocytes and motor neurons in ALS.Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice.Pediatric gliomas as neurodevelopmental disorders MADM gives new insights into gliomagenesis.Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma.Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies.Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma.Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.E2F1 coregulates cell cycle genes and chromatin components during the transition of oligodendrocyte progenitors from proliferation to differentiation.Network Plasticity and Intraoperative Mapping for Personalized Multimodal Management of Diffuse Low-Grade Gliomas.Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.

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Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype

http://www.wikidata.org/entity/Q33916126

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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Glioblastoma models reveal the ...... rs and the proneural phenotype

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Adam M Sonabend

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Craig Soderquist

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Jeffrey N Bruce

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Liang Lei

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Paolo Guarnieri

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Bioconductor: open software development for computational biology and bioinformatics

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme

Database resources of the National Center for Biotechnology Information

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

An integrated genomic analysis of human glioblastoma multiforme

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

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