Molecular basis of alanine discrimination in editing site
about
Exome sequencing identifies mitochondrial alanyl-tRNA synthetase mutations in infantile mitochondrial cardiomyopathyThe structure of alanyl-tRNA synthetase with editing domainUnique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerizationThe C-Ala Domain Brings Together Editing and Aminoacylation Functions on One tRNAParadox of mistranslation of serine for alanine caused by AlaRS recognition dilemmaAn Appended Domain Results in an Unusual Architecture for Malaria Parasite Tryptophanyl-tRNA SynthetaseA genomic glimpse of aminoacyl-tRNA synthetases in malaria parasite Plasmodium falciparumUnusual domain architecture of aminoacyl tRNA synthetases and their paralogs from Leishmania majorMistranslation and its control by tRNA synthetases.Substrate-mediated fidelity mechanism ensures accurate decoding of proline codons.Ancestral AlaX editing enzymes for control of genetic code fidelity are not tRNA-specific.Mechanism of tRNA-dependent editing in translational quality controlUneven spread of cis- and trans-editing aminoacyl-tRNA synthetase domains within translational compartments of P. falciparum.Substrate specificity of bacterial prolyl-tRNA synthetase editing domain is controlled by a tunable hydrophobic pocketStructural analyses clarify the complex control of mistranslation by tRNA synthetasesSpecificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.Crystallization and preliminary X-ray crystallographic study of alanyl-tRNA synthetase from the archaeon Archaeoglobus fulgidusAminoacyl-tRNA synthetases as drug targets in eukaryotic parasites.Mapping hidden potential identity elements by computing the average discriminating power of individual tRNA positions.Role of D-aminoacyl-tRNA deacylase beyond chiral proofreading as a cellular defense against glycine mischarging by AlaRS.Substrate specificity and catalysis by the editing active site of Alanyl-tRNA synthetase from Escherichia coli.Natural homolog of tRNA synthetase editing domain rescues conditional lethality caused by mistranslation.Interdomain communication modulates the tRNA-dependent pre-transfer editing of leucyl-tRNA synthetase.Conformational and chemical selection by a trans-acting editing domain.
P2860
Q24301657-8E8E9504-A60A-4D4E-9A20-BFF146FD9251Q27643956-8ACB04D6-28BE-4CC6-8BC7-863369BCCE66Q27655412-1FA9EAB2-7BFF-4425-AFF9-1C4B4E142AE9Q27656913-30CCAD36-A234-4064-88BA-C65DBF82E09CQ27658655-EBD69398-558A-4453-B572-A18D410D0181Q27678690-482A4AA3-0103-427B-A728-9381A558AFECQ27972876-F2888DE9-0021-4B3A-8F8D-1867B314C83FQ34476623-D6342E8A-EF59-47BB-AFFB-EF0D94DD7179Q35173034-28FA7A00-40B0-408D-9EB0-436FF9FB32C3Q35213173-3E1D0561-D432-4411-B673-E0BAE8202C61Q35451324-706ACE68-0DE8-4F54-A533-6EB8108D0FC1Q35576074-594FB179-1AB9-4B04-8338-C547169E1275Q35619612-9E2314A5-C39C-476C-A82B-BC8E93E574FDQ35728198-AED5D2F0-AF2A-46E3-9A95-1469164B5B45Q35784913-98CD245C-9EF6-45C2-AA00-BF4E7FC6FABFQ35818989-C690985E-8927-435A-A7CC-C5F812DFA2D7Q36580552-5E9A2DAE-5CB5-4BDD-9F8B-986472345975Q37613101-70CCAE70-224A-483B-B66B-C1BAAA4D4ED6Q42196972-6CC117A6-C066-47E7-9FF3-0751EDC00A63Q42290156-5DCF7E43-D73B-44DA-BD8E-4E13DB95409FQ42709395-6D1AFA84-9BE2-4A5F-9444-8E67AD45E0FBQ43251134-89B9A7D9-2F38-44B7-A47A-DE5488BEC004Q44478323-B717132D-57BB-4AAC-8A3F-2D5A0AF9B45EQ47998651-27DDF068-8BB8-4722-9987-CFC9C160E1B3
P2860
Molecular basis of alanine discrimination in editing site
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Molecular basis of alanine discrimination in editing site
@ast
Molecular basis of alanine discrimination in editing site
@en
type
label
Molecular basis of alanine discrimination in editing site
@ast
Molecular basis of alanine discrimination in editing site
@en
prefLabel
Molecular basis of alanine discrimination in editing site
@ast
Molecular basis of alanine discrimination in editing site
@en
P2093
P2860
P356
P1476
Molecular basis of alanine discrimination in editing site
@en
P2093
Ayuko Okada
Isao Tanaka
Masaaki Sokabe
Takashi Nakashima
P2860
P304
11669-11674
P356
10.1073/PNAS.0502119102
P407
P577
2005-08-08T00:00:00Z