HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.
about
Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1Lhx2 expression promotes self-renewal of a distinct multipotential hematopoietic progenitor cell in embryonic stem cell-derived embryoid bodiesES-cell derived hematopoietic cells induce transplantation tolerance.Biologic properties and enucleation of red blood cells from human embryonic stem cellsAutologous blood cell therapies from pluripotent stem cells.Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation.Hemgn is a direct transcriptional target of HOXB4 and induces expansion of murine myeloid progenitor cells.Downstream targets of HOXB4 in a cell line model of primitive hematopoietic progenitor cellsEmbryonic stem cell-derived hematopoietic stem cells.TAT-mediated transduction of NF-Ya peptide induces the ex vivo proliferation and engraftment potential of human hematopoietic progenitor cells.The HOXB4 homeoprotein promotes the ex vivo enrichment of functional human embryonic stem cell-derived NK cellsErythropoiesis: development and differentiation.USF1 and hSET1A mediated epigenetic modifications regulate lineage differentiation and HoxB4 transcription.Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells.Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells.Mapping mouse hemangioblast maturation from headfold stages.Dynamic HoxB4-regulatory network during embryonic stem cell differentiation to hematopoietic cells.HOXB4's road map to stem cell expansion.Designer blood: creating hematopoietic lineages from embryonic stem cells.Hematopoiesis and immunity of HOXB4-transduced embryonic stem cell-derived hematopoietic progenitor cells.High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vectorHOXB4 and retroviral vectors: adding fuel to the fire.Progress and prospects: gene transfer into embryonic stem cells.RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cellsReprogrammed cells for disease modeling and regenerative medicine.Serum- and stromal cell-free hypoxic generation of embryonic stem cell-derived hematopoietic cells in vitro, capable of multilineage repopulation of immunocompetent mice.Stem cell sources and therapeutic approaches for central nervous system and neural retinal disorders.Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells.Generation of mesenchymal stromal cells from HOXB4-expressing human embryonic stem cells.Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusionsA conserved role for Hox paralog group 4 in regulation of hematopoietic progenitors.Immunity of embryonic stem cell-derived hematopoietic progenitor cells.Experimental limitations using reprogrammed cells for hematopoietic differentiation.Mechanism of action of HOXB4 on the hematopoietic differentiation of embryonic stem cells.HOXB4 Increases Runx1 Expression to Promote the de novo Formation of Multipotent Hematopoietic Cells.Efficient production of T cells from mouse pluripotent stem cells by controlled expression of Lhx2.Improved lentiviral gene transfer into human embryonic stem cells grown in co-culture with murine feeder and stroma cells.HOXB4 but not BMP4 confers self-renewal properties to ES-derived hematopoietic progenitor cells.Ectopic expression of Hoxb4a in hemangioblasts promotes hematopoietic development in early embryogenesis of zebrafish.In Vitro Generation of Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature from Murine Induced Pluripotent Stem Cells.
P2860
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P2860
HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.
@ast
HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.
@en
type
label
HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.
@ast
HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.
@en
prefLabel
HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.
@ast
HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.
@en
P2093
P2860
P356
P1476
HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells
@en
P2093
Andreas Mairhofer
Bernhard Schiedlmeier
Christopher Baum
Hartmut Beug
Kenji Kamino
Peter Steinlein
Sandra Pilat
Sebastian Carotta
Ute Modlich
P2860
P304
12101-12106
P356
10.1073/PNAS.0505624102
P407
P50
P577
2005-08-10T00:00:00Z