Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions
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A functional screen to identify novel effectors of hematopoietic stem cell activityCandidate genes for expansion and transformation of hematopoietic stem cells by NUP98-HOX fusion genes.Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid LeukemiaMedicine. The blood stem cell Holy Grail?Delineating domains and functions of NUP98 contributing to the leukemogenic activity of NUP98-HOX fusionsCytokine-regulated GADD45G induces differentiation and lineage selection in hematopoietic stem cells.Comprehensive microRNA expression profiling of the hematopoietic hierarchy.Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cellsOntogeny stage-independent and high-level clonal expansion in vitro of mouse hematopoietic stem cells stimulated by an engineered NUP98-HOX fusion transcription factorDifferential effects of HOXB4 and NUP98-HOXA10hd on hematopoietic repopulating cells in a nonhuman primate model.Increased Engraftment of Human Short Term Repopulating Hematopoietic Cells in NOD/SCID/IL2rγnull Mice by Lentiviral Expression of NUP98-HOXA10HDA role for GPx3 in activity of normal and leukemia stem cellsOncogenic NRAS hyper-activates multiple pathways in human cord blood stem/progenitor cells and promotes myelomonocytic proliferation in vivo.Ex vivo expansion of normal and chronic myeloid leukemic stem cells without functional alteration using a NUP98HOXA10homeodomain fusion gene.Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia.RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.Concise review: Multidimensional regulation of the hematopoietic stem cell state.Optimizing autologous cell grafts to improve stem cell gene therapy.The roles of the nuclear pore complex in cellular dysfunction, aging and disease.The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia.Lentiviral Transfer of γ-Globin with Fusion Gene NUP98-HOXA10HD Expands Hematopoietic Stem Cells and Ameliorates Murine β-Thalassemia.NUP98-HOXA10hd-expanded hematopoietic stem cells efficiently reconstitute bone marrow of mismatched recipients and induce tolerance.Brief report: ectopic expression of NUP98-HOXA10 augments erythroid differentiation of human embryonic stem cells.High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays.A Prospective Analysis of Human Leukemogenesis
P2860
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P2860
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on May 2007
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions
@en
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions.
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type
label
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions
@en
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions.
@nl
prefLabel
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions
@en
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions.
@nl
P2093
P2860
P1476
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions
@en
P2093
Clayton Smith
Connie J Eaves
Guy Sauvageau
Hideaki Ohta
Maura Gasparetto
Nicolas Pineault
Sanja Sekulovic
Silvia Bakovic
P2860
P304
P356
10.1016/J.EXPHEM.2007.02.012
P577
2007-05-01T00:00:00Z