The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. - Wikidata - wikimedia - TriplyDB

The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

http://www.wikidata.org/entity/Q33928657

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Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation Phosphorylation of Grb14 BPS domain by GSK-3 correlates with complex forming of Grb14 and insulin receptor mTOR signaling in growth control and disease The role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistance Inhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and Beyond The role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancer Regulation of global and specific mRNA translation by the mTOR signaling pathway Recent findings and technological advances in phosphoproteomics for cells and tissues Insulin receptor signaling in normal and insulin-resistant states MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?Status of large-scale analysis of post-translational modifications by mass spectrometry Novel targeting of phosphatidylinositol 3-kinase and mammalian target of rapamycin in renal cell carcinoma Regulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteins Regulation of cardiac proteasomes by ubiquitination, SUMOylation, and beyond mTOR-dependent cell survival mechanisms Leucine and mTORC1: a complex relationship Mass spectrometry-based detection and assignment of protein posttranslational modifications Roles of the PI3K/Akt pathway in Epstein-Barr virus-induced cancers and therapeutic implications Nutrient sensing, metabolism, and cell growth control Regulation of mTORC1 by amino acids The expanding role of mTOR in cancer cell growth and proliferation Metabolic maintenance of cell asymmetry following division in activated T lymphocytes Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin mTOR kinase structure, mechanism and regulation The Crystal Structure of Six-transmembrane Epithelial Antigen of the Prostate 4 (Steap4), a Ferri/Cuprireductase, Suggests a Novel Interdomain Flavin-binding Site Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives Role of the mammalian target of rapamycin pathway in lentiviral vector transduction of hematopoietic stem cells The secretory pathway kinases The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence Protor-2 interacts with tristetraprolin to regulate mRNA stability during stress La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)mTOR signaling in tumorigenesis TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2 Signaling by the phosphoinositide 3-kinase family in immune cells Rapalogs and mTOR inhibitors as anti-aging therapeutics Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2)

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The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

http://www.wikidata.org/entity/Q33928657

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

The mTOR-regulated phosphoprot ...... on of growth factor signaling.

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The mTOR-regulated phosphoprot ...... on of growth factor signaling.

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The mTOR-regulated phosphoprot ...... on of growth factor signaling.

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The mTOR-regulated phosphoprot ...... on of growth factor signaling.

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The mTOR-regulated phosphoprot ...... on of growth factor signaling.

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SCIENCE.1199498

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The mTOR-regulated phosphoprot ...... ion of growth factor signaling

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Daniel Lim

http://www.w3.org/2001/XMLSchema#string

Jarrod A Marto

http://www.w3.org/2001/XMLSchema#string

Jonathan Rameseder

http://www.w3.org/2001/XMLSchema#string

Kathleen A Ottina

http://www.w3.org/2001/XMLSchema#string

Michael B Yaffe

http://www.w3.org/2001/XMLSchema#string

Nathanael S Gray

http://www.w3.org/2001/XMLSchema#string

Peggy P Hsu

http://www.w3.org/2001/XMLSchema#string

Seong A Kang

http://www.w3.org/2001/XMLSchema#string

Timothy R Peterson

http://www.w3.org/2001/XMLSchema#string

Yi Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase

Nedd4 controls animal growth by regulating IGF-1 signaling

mTOR: from growth signal integration to cancer, diabetes and ageing

C. elegans La-related protein, LARP-1, localizes to germline P bodies and attenuates Ras-MAPK signaling during oogenesis

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.

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1317-1322

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scholarly article

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10.1126/SCIENCE.1199498

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6035

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332

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David M Sabatini

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2011-06-01T00:00:00Z

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51207092

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21659604

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3177140

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