GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line
about
The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiationPioneer transcription factors: establishing competence for gene expressionNegative cross-talk between hematopoietic regulators: GATA proteins repress PU.1Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOGTwo cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteinsGATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line.GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood progenitors.Transcription factor-mediated lineage switching reveals plasticity in primary committed progenitor cells.Cellular phenotype switching and microvesicles.Direct lineage conversions: unnatural but useful?A blueprint for engineering cell fate: current technologies to reprogram cell identity.Erythropoietin triggers a burst of GATA-1 in normal human erythroid cells differentiating in tissue culture.A GATA-2/estrogen receptor chimera functions as a ligand-dependent negative regulator of self-renewalAntagonism between C/EBPbeta and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitorsAntisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo.Inhibition of hematopoiesis by competitive binding of transcription factor PU.1.GATA transcription factors associate with a novel class of nuclear bodies in erythroblasts and megakaryocytes.A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation.Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1.Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient micePU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiationAn upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic miceLoss of erythropoietin responsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming geneAntagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage.Self-association of the erythroid transcription factor GATA-1 mediated by its zinc finger domainsErythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line.Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinaseA regulatory interplay between miR-27a and Runx1 during megakaryopoiesisInhibition of all-trans retinoic acid-induced granulocytic differentiation of WEHI-3B D+ cells by forced expression of SCL (TAL1) and GATA-1.Reprogramming cell fate: a changing story.Regulation of the genetic code in megakaryocytes and platelets.GATA-1 dominantly activates a program of erythroid gene expression in factor-dependent myeloid FDCW2 cells.Immortalization of multipotent growth-factor dependent hemopoietic progenitors from mice transgenic for GATA-1 driven SV40 tsA58 gene.Functional domains of alpha-catenin required for the strong state of cadherin-based cell adhesionRegulation of J6 gene expression by transcription factor GATA-4.Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest.alpha-catenin-deficient F9 cells differentiate into signet ring cells.Identification of a functional transcriptional factor AP-1 site in the sheep interferon tau gene that mediates a response to PMA in JEG3 cellsTranscriptional and Microenvironmental Regulation of Lineage Ambiguity in Leukemia.
P2860
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P2860
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line
description
1992 nî lūn-bûn
@nan
1992 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line
@ast
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line
@en
type
label
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line
@ast
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line
@en
prefLabel
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line
@ast
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line
@en
P2093
P2860
P1433
P1476
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line
@en
P2093
A G Elefanty
J E Visvader
P2860
P304
P407
P577
1992-12-01T00:00:00Z