Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest.
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Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesisFunctional interactions among members of the MAX and MLX transcriptional network during oncogenesisOlean-12-eno[2,3-c] [1,2,5]oxadiazol-28-oic acid (OEOA) induces G1 cell cycle arrest and differentiation in human leukemia cell linesBrachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathwayHigh p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycleGfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells.Immortalization of erythroblasts by c-MYC and BCL-XL enables large-scale erythrocyte production from human pluripotent stem cellsDown-regulation of Myc is essential for terminal erythroid maturationExogenous c-Myc Blocks Differentiation and Improves Expansion of Human Erythroblasts In vitro.MYCN transgenic zebrafish model with the characterization of acute myeloid leukemia and altered hematopoiesis.SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27(KIP1) through SKP2 in human leukemia cells.Myc roles in hematopoiesis and leukemiahERG potassium channel blockage by scorpion toxin BmKKx2 enhances erythroid differentiation of human leukemia cells K562Role of helix-loop-helix proteins during differentiation of erythroid cells.BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis.p27kip1 maintains a subset of leukemia stem cells in the quiescent state in murine MLL-leukemia.MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma.Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.MYC oncogene in myeloid neoplasias.p27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes.MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.).Hypoxia-inducible factor-1alpha blocks differentiation of malignant gliomas.Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1.p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes.MYC accelerates p21CIP-induced megakaryocytic differentiation involving early mitosis arrest in leukemia cells.GATA4 loss of function in liver cancer impedes precursor to hepatocyte transition.Detecting Markers of Therapy-Induced Senescence in Cancer Cells.Differentiation therapy and the mechanisms that terminate cancer cell proliferation without harming normal cells
P2860
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P2860
Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Myc inhibits p27-induced eryth ...... 27-mediated cell cycle arrest.
@en
type
label
Myc inhibits p27-induced eryth ...... 27-mediated cell cycle arrest.
@en
prefLabel
Myc inhibits p27-induced eryth ...... 27-mediated cell cycle arrest.
@en
P2093
P2860
P356
P1476
Myc inhibits p27-induced eryth ...... 27-mediated cell cycle arrest.
@en
P2093
Brenda O'Connell
Carlos Richard
Gabriel Bretones
John Sedivy
M Dolores Delgado
Nuria Ferrándiz
Rosa Blanco
Verónica Torrano
P2860
P304
P356
10.1128/MCB.00752-08
P407
P577
2008-10-06T00:00:00Z