Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis
about
Extensions of MADM (mosaic analysis with double markers) in miceModeling chromosomes in mouse to explore the function of genes, genomic disorders, and chromosomal organizationTwo decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.MLL fusions: pathways to leukemiaMouse chromosome engineering for modeling human disease.RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction.Cancer genetics of epigenetic genes.Mechanisms of transcription factor deregulation in lymphoid cell transformation.MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.Chromosomal translocations among the healthy human population: implications in oncogenesis.Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.Molecular mechanisms of MLL-associated leukemia.Somatic Engineering of Oncogenic Chromosomal Rearrangements: A PerspectiveMLL-ENL-mediated leukemia initiation at the interface of lymphoid commitment.Mouse models of MLL leukemia: recapitulating the human diseaseModeling human MLL-AF9 translocated acute myeloid leukemia from single donors reveals RET as a potential therapeutic target.Dysregulation of haematopoietic stem cell regulatory programs in acute myeloid leukaemia.Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors.Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model.Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation.Human MLL-AF9 Overexpression Induces Aberrant Hematopoietic Expansion in Zebrafish.
P2860
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P2860
Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Mll fusions generated by Cre-l ...... reassignment in tumorigenesis
@ast
Mll fusions generated by Cre-l ...... reassignment in tumorigenesis
@en
Mll fusions generated by Cre-l ...... reassignment in tumorigenesis
@en-gb
type
label
Mll fusions generated by Cre-l ...... reassignment in tumorigenesis
@ast
Mll fusions generated by Cre-l ...... reassignment in tumorigenesis
@en
Mll fusions generated by Cre-l ...... reassignment in tumorigenesis
@en-gb
prefLabel
Mll fusions generated by Cre-l ...... reassignment in tumorigenesis
@ast
Mll fusions generated by Cre-l ...... reassignment in tumorigenesis
@en
Mll fusions generated by Cre-l ...... reassignment in tumorigenesis
@en-gb
P2093
P2860
P356
P1433
P1476
Mll fusions generated by Cre-l ...... reassignment in tumorigenesis
@en
P2093
Alan Forster
Angelika Daser
Florencia Cano
Lesley F Drynan
Nicole M M Chan
Richard Pannell
P2860
P304
P356
10.1038/SJ.EMBOJ.7600760
P407
P577
2005-08-11T00:00:00Z