Mechanisms of transcription factor deregulation in lymphoid cell transformation.
about
NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemiaDifferential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineagesErythro-megakaryocytic transcription factors associated with hereditary anemiaWogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesisGenetic and environmental pathways to complex diseases.NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells.Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complexInterconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemiaMutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA binding.Mediator subunit 12 is required for neutrophil development in zebrafishCharacterisation of genome-wide PLZF/RARA target genes.Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemiaNotch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1-associated adult T-cell leukemia.Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic miceT-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell.Targeting transcription regulation in cancer with a covalent CDK7 inhibitorUpregulation of DLX5 promotes ovarian cancer cell proliferation by enhancing IRS-2-AKT signaling.Activation of proto-oncogenes by disruption of chromosome neighborhoods.Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cellsSLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signatureIdentification of highly methylated genes across various types of B-cell non-hodgkin lymphoma.HTLV-1 HBZ protein deregulates interactions between cellular factors and the KIX domain of p300/CBP.A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets.Dominant-negative mechanism of leukemogenic PAX5 fusions.Myc proteins in brain tumor development and maintenance.The two faces of FBW7 in cancer drug resistance.MYC rearrangement involving a novel non-immunoglobulin chromosomal locus in precursor B-cell acute lymphoblastic leukemia.Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrityRegulation of immune responses and tolerance: the microRNA perspective.Inferring chromatin-bound protein complexes from genome-wide binding assaysWT1 mutations in T-ALLGenomic tools for dissecting oncogenic transcriptional networks in human leukemia.DNA secondary structures and epigenetic determinants of cancer genome evolution.Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia.The versatility of haematopoietic stem cells: implications for leukaemia.The versatile landscape of haematopoiesis: are leukaemia stem cells as versatile?Mechanisms of programmed DNA lesions and genomic instability in the immune system.Validation and implementation of a method for microarray gene expression profiling of minor B-cell subpopulations in man
P2860
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P2860
Mechanisms of transcription factor deregulation in lymphoid cell transformation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Mechanisms of transcription factor deregulation in lymphoid cell transformation.
@en
type
label
Mechanisms of transcription factor deregulation in lymphoid cell transformation.
@en
prefLabel
Mechanisms of transcription factor deregulation in lymphoid cell transformation.
@en
P2860
P356
P1433
P1476
Mechanisms of transcription factor deregulation in lymphoid cell transformation.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210766
P407
P577
2007-10-01T00:00:00Z