Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase.
about
Is the oxidative stress theory of aging dead?A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genesWortmannin reduces insulin signaling and death in seizure-prone Pcmt1-/- miceThe interplay between protein L-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegansCrystal structure of human L-isoaspartyl methyltransferaseRegulation of protein L-isoaspartyl methyltransferase by cell-matrix interactions: involvement of integrin alphavbeta3, PI 3-kinase, and the proteasomeRegulation of longevity by regulator of G-protein signaling protein, LocoIntegrated proteomic analysis of major isoaspartyl-containing proteins in the urine of wild type and protein L-isoaspartate O-methyltransferase-deficient mice.Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speedA naturally occurring polymorphism at Drosophila melanogaster Lim3 Locus, a homolog of human LHX3/4, affects Lim3 transcription and fly lifespan.Non-repair pathways for minimizing protein isoaspartyl damage in the yeast Saccharomyces cerevisiae.Isoaspartyl formation in creatine kinase B is associated with loss of enzymatic activity; implications for the linkage of isoaspartate accumulation and neurological dysfunction in the PIMT knockout mouse.Drosophila as a model for age-related impairment in locomotor and other behaviorsProtective effect of borage seed oil and gamma linolenic acid on DNA: in vivo and in vitro studiesOverexpression of methionine-R-sulfoxide reductases has no influence on fruit fly aging.Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogasterLoco signaling pathway in longevity.The cloning and characterization of the histone acetyltransferase human homolog Dmel\TIP60 in Drosophila melanogaster: Dmel\TIP60 is essential for multicellular developmentIdentification of de novo synthesized and relatively older proteins: accelerated oxidative damage to de novo synthesized apolipoprotein A-1 in type 1 diabetesThe L-isoaspartyl-O-methyltransferase in Caenorhabditis elegans larval longevity and autophagy.Heart-specific Rpd3 downregulation enhances cardiac function and longevity.Developmental expression of drop-dead is required for early adult survival and normal body mass in Drosophila melanogasterDeamidation: Differentiation of aspartyl from isoaspartyl products in peptides by electron capture dissociation.Protein L-isoaspartyl methyltransferase regulates p53 activity.The protein L-isoaspartyl-O-methyltransferase functions in the Caenorhabditis elegans stress responseGenes encoding longevity: from model organisms to humans.Protein-repair and hormone-signaling pathways specify dauer and adult longevity and dauer development in Caenorhabditis elegans.Critical role of protein L-isoaspartyl methyltransferase in basic fibroblast growth factor-mediated neuronal cell differentiation.The V119I polymorphism in protein L-isoaspartate O-methyltransferase alters the substrate-binding interface.Thioredoxin, oxidative stress, cancer and aging.Hsa-miR-195 targets PCMT1 in hepatocellular carcinoma that increases tumor life span.Proteostasis and aging.Future of the Genetic Code.Detergents: Friends not foes for high-performance membrane proteomics toward precision medicine.Role of citrus juices and distinctive components in the modulation of degenerative processes: genotoxicity, antigenotoxicity, cytotoxicity, and longevity in Drosophila.Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain.Drosophila nervous system as a target of aging and anti-aging interventions.Defective responses to oxidative stress in protein l-isoaspartyl repair-deficient Caenorhabditis elegans.Overexpression of L-isoaspartate O-methyltransferase in Escherichia coli increases heat shock survival by a mechanism independent of methyltransferase activity.Functional conservatism among Drosophila simulans flies experiencing different thermal regimes and mitochondrial DNA introgression.
P2860
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P2860
Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase.
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Extension of the Drosophila li ...... tein repair methyltransferase.
@ast
Extension of the Drosophila li ...... tein repair methyltransferase.
@en
type
label
Extension of the Drosophila li ...... tein repair methyltransferase.
@ast
Extension of the Drosophila li ...... tein repair methyltransferase.
@en
prefLabel
Extension of the Drosophila li ...... tein repair methyltransferase.
@ast
Extension of the Drosophila li ...... tein repair methyltransferase.
@en
P2093
P2860
P356
P1476
Extension of the Drosophila li ...... tein repair methyltransferase.
@en
P2093
C M O'Connor
D A Chavous
F R Jackson
P2860
P304
14814-14818
P356
10.1073/PNAS.251446498
P407
P577
2001-12-11T00:00:00Z