Native-like aggregates of factor VIII are immunogenic in von Willebrand factor deficient and hemophilia a mice
about
Effects of replacement of factor VIII amino acids Asp519 and Glu665 with Val on plasma survival and efficacy in vivo.Soy phosphatidylinositol containing nanoparticle prolongs hemostatic activity of B-domain deleted factor VIII in hemophilia A mice.Immunogenicity of subcutaneously administered therapeutic proteins--a mechanistic perspective.Minimizing immunogenicity of biopharmaceuticals by controlling critical quality attributes of proteins.Physical Characterization and Innate Immunogenicity of Aggregated Intravenous Immunoglobulin (IGIV) in an In Vitro Cell-Based Model.Mouse Models for Assessing Protein Immunogenicity: Lessons and Challenges.The Role of Aggregates of Therapeutic Protein Products in Immunogenicity: An Evaluation by Mathematical Modeling.Microparticles and Nanoparticles Delivered in Intravenous Saline and in an Intravenous Solution of a Therapeutic Antibody Product.Challenges and Opportunities for the Subcutaneous Delivery of Therapeutic Proteins.
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Native-like aggregates of factor VIII are immunogenic in von Willebrand factor deficient and hemophilia a mice
description
article científic
@ca
article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 02 March 2012
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Native-like aggregates of fact ...... eficient and hemophilia a mice
@en
Native-like aggregates of fact ...... ficient and hemophilia a mice.
@nl
type
label
Native-like aggregates of fact ...... eficient and hemophilia a mice
@en
Native-like aggregates of fact ...... ficient and hemophilia a mice.
@nl
prefLabel
Native-like aggregates of fact ...... eficient and hemophilia a mice
@en
Native-like aggregates of fact ...... ficient and hemophilia a mice.
@nl
P2093
P2860
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P356
P1476
Native-like aggregates of fact ...... eficient and hemophilia a mice
@en
P2093
C Russell Middaugh
Dipak S Pisal
Matthew P Kosloski
Richard B Bankert
Sathy V Balu-Iyer
P2860
P304
P356
10.1002/JPS.23091
P407
P577
2012-03-02T00:00:00Z