sli-1, a negative regulator of let-23-mediated signaling in C. elegans
about
Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicityAn AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signaling during C. elegans vulva inductionc-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptorThe adaptor protein soc-1/Gab1 modifies growth factor receptor output in Caenorhabditis elegans.Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding.Recent developments in lymphocyte activation: linking kinases to downstream signaling events.Caenorhabditis elegans SUR-5, a novel but conserved protein, negatively regulates LET-60 Ras activity during vulval induction.Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient miceCancer models in Caenorhabditis elegans.A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling.RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegansSLI-1 Cbl inhibits the engulfment of apoptotic cells in C. elegans through a ligase-independent functionPathway to RAS.The promotion of gonadal cell divisions by the Caenorhabditis elegans TRPM cation channel GON-2 is antagonized by GEM-4 copineCbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversionVersatile roles of k63-linked ubiquitin chains in trafficking.Requirements of multiple domains of SLI-1, a Caenorhabditis elegans homologue of c-Cbl, and an inhibitory tyrosine in LET-23 in regulating vulval differentiation.Identification and classification of genes that act antagonistically to let-60 Ras signaling in Caenorhabditis elegans vulval development.Caenorhabditis elegans SOS-1 is necessary for multiple RAS-mediated developmental signals.sli-3 negatively regulates the LET-23/epidermal growth factor receptor-mediated vulval induction pathway in Caenorhabditis elegans.An activating mutation in sos-1 identifies its Dbl domain as a critical inhibitor of the epidermal growth factor receptor pathway during Caenorhabditis elegans vulval development.Cbl-3-deficient mice exhibit normal epithelial developmentc-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses.A point mutation in the extracellular domain activates LET-23, the Caenorhabditis elegans epidermal growth factor receptor homolog.Coordinated morphogenesis of epithelia during development of the Caenorhabditis elegans uterine-vulval connection.Positive and negative tissue-specific signaling by a nematode epidermal growth factor receptor.Membrane protein targeting to the MVB/lysosome.Dynein-mediated trafficking negatively regulates LET-23 EGFR signaling.A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.From phenologs to silent suppressors: Identifying potential therapeutic targets for human disease.The C. elegans homolog of the mammalian tumor suppressor Dep-1/Scc1 inhibits EGFR signaling to regulate binary cell fate decisions.
P2860
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P2860
sli-1, a negative regulator of let-23-mediated signaling in C. elegans
description
1995 nî lūn-bûn
@nan
1995 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
sli-1, a negative regulator of let-23-mediated signaling in C. elegans
@ast
sli-1, a negative regulator of let-23-mediated signaling in C. elegans
@en
type
label
sli-1, a negative regulator of let-23-mediated signaling in C. elegans
@ast
sli-1, a negative regulator of let-23-mediated signaling in C. elegans
@en
prefLabel
sli-1, a negative regulator of let-23-mediated signaling in C. elegans
@ast
sli-1, a negative regulator of let-23-mediated signaling in C. elegans
@en
P2093
P2860
P1433
P1476
sli-1, a negative regulator of let-23-mediated signaling in C. elegans
@en
P2093
G D Jongeward
P W Sternberg
T R Clandinin
P2860
P304
P407
P577
1995-04-01T00:00:00Z