Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways
about
Cloning and characterization of a family of proteins associated with MplProtein-arginine methyltransferase 1 suppresses megakaryocytic differentiation via modulation of the p38 MAPK pathway in K562 cellsIEX-1: a new ERK substrate involved in both ERK survival activity and ERK activationExtracellular signal-regulated kinase induces the megakaryocyte GPIIb/CD41 gene through MafB/KreislerMultiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functionsStimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cellsA critical function for B-Raf at multiple stages of myelopoiesisC3G regulates the size of the cerebral cortex neural precursor populationSustained activation of extracellular signal-regulated kinase by nerve growth factor regulates c-fos protein stabilization and transactivation in PC12 cells.The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model.MegakaryopoiesisThrombocytopenia in MDS: epidemiology, mechanisms, clinical consequences and novel therapeutic strategies.Use of a thrombopoietin receptor agonist in von Willebrand disease type 2B (p.V1316M) with severe thrombocytopenia and intracranial hemorrhage.Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis.JAK2 and MPL protein levels determine TPO-induced megakaryocyte proliferation vs differentiation.Autocrine role of angiopoietins during megakaryocytic differentiationSpred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic cells.STAT5 and Oct-1 form a stable complex that modulates cyclin D1 expression.cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinomacAMP/PKA-mediated regulation of erythropoiesis.A novel role for Cdk1/cyclin B in regulating B-raf activation at mitosisExtracellular calcium elicits feedforward regulation of the Toll-like receptor-triggered innate immune response.Vasoactive intestinal peptide upregulates MUC2 intestinal mucin via CREB/ATF1.Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription.Raf-MEK-Erk cascade in anoikis is controlled by Rac1 and Cdc42 via Akt.Growth factor receptor-bound protein 2 contributes to (hem)immunoreceptor tyrosine-based activation motif-mediated signaling in platelets.Selective modification of eukaryotic initiation factor 4F (eIF4F) at the onset of cell differentiation: recruitment of eIF4GII and long-lasting phosphorylation of eIF4E.MPL W515L expression induces TGFβ secretion and leads to an increase in chemokinesis via phosphorylation of THOC5.Platelet ERK2 activation by thrombin is dependent on calcium and conventional protein kinases C but not Raf-1 or B-Raf.Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma.Treprostinil inhibits the adhesion and differentiation of fibrocytes via the cyclic adenosine monophosphate-dependent and Ras-proximate protein-dependent inactivation of extracellular regulated kinase.sst2 Somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 activation.Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.Multiple signaling pathways are involved in endothelin-1-induced brain endothelial cell migration.Mutation in RAP1 is a rare event in myelodysplastic syndromes.Integrated Network Pharmacology and Metabolomics Analysis of the Therapeutic Effects of Zi Dian Fang on Immune Thrombocytopenic Purpura.
P2860
Q24292135-6D995C28-8439-4660-A99E-E828F9A1EF53Q24310063-19335D9A-3157-4BA3-8FCB-6144C0299547Q24534869-75DD5967-DBFA-4484-A3E6-6AAB39E55594Q24567630-06CB4EFE-CE18-4B14-936C-C1277517E44EQ28115996-667D4040-7698-4463-BB66-4DA7B4C6B914Q28513370-A4306207-0B20-456A-9530-5BC6CB068613Q28590150-5829A88B-511E-4FFC-823C-26E5C5CC096AQ28591929-0B882D61-6A62-4F61-AE7B-D4A821D9DC59Q30359233-DC41A2EE-3415-453B-9CD1-D6B50F81D6CEQ33383707-BEE85C55-53CC-4756-9E54-3722171BFFE8Q33390616-B2D48A13-2B3C-4ADC-8FE0-2D095119FE51Q33427023-189D7175-3101-49B2-9F13-08CD9243AA87Q33437102-368F3218-565C-4FAB-8F9D-F37EEDCBABE4Q33495581-F53F342C-EC52-404A-9000-4390DBCCDC82Q34282328-B508ADE7-9AD5-47AD-973F-3E2540A0EE03Q34293019-77AFBF60-22DA-4AA7-B084-33629A1998B7Q34335730-36967D43-DC1A-47D1-91EA-78F8A6B00842Q34355754-8A013393-C3C1-4882-B871-5658EB5A0C37Q34985773-96A6AD16-5C18-46B4-9567-316087827B0CQ35161430-A4F9CD26-72FC-4E23-ACFE-452DB0293713Q35635556-5673DF7B-1CBB-4CC6-B8BB-9313C346ADC7Q36739904-0F28BA28-6AE2-460E-9D39-788E3182E764Q37634931-1AF218B8-8F4D-4DC5-AB06-36A62DF670CBQ38319884-FB649326-E9A0-47B7-B717-4307660C49F5Q39332914-776EC89C-5BE6-48B8-9DC5-1EC1D320D324Q39528226-9C993BD5-ECFB-494F-8FEC-83CB1B933FB0Q39857872-F7482FD1-B8E0-4281-9444-DAB115C15A8FQ40886501-E72934E2-6CEA-4D3F-A482-36F9C69E6058Q41787058-8508DF60-DDE8-4994-8CC9-D391A90B6414Q42527926-35F45575-3C56-49F0-89D3-73CB42C7F45CQ43005729-CC6E459F-4CF6-4CC7-AC90-F29260EAFFBAQ43739195-94CA7B81-D5D6-4237-98EA-82DFF8E7B261Q44524136-4510606A-D5BD-40F6-8AC4-BFF3441A686DQ44714830-00560BDC-0C5C-44D8-A2AA-5C999E4D5AC6Q46923162-A1DBFBA0-19D6-4D9F-BB17-D3CBD429AA10Q54647172-659545D6-467B-425E-B09C-88C66AAA925FQ55444585-F787EAF4-ABDC-4E76-B338-004169AB1D4E
P2860
Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Thrombopoietin-mediated sustai ...... Rap1-B-Raf-dependent pathways
@ast
Thrombopoietin-mediated sustai ...... Rap1-B-Raf-dependent pathways
@en
type
label
Thrombopoietin-mediated sustai ...... Rap1-B-Raf-dependent pathways
@ast
Thrombopoietin-mediated sustai ...... Rap1-B-Raf-dependent pathways
@en
prefLabel
Thrombopoietin-mediated sustai ...... Rap1-B-Raf-dependent pathways
@ast
Thrombopoietin-mediated sustai ...... Rap1-B-Raf-dependent pathways
@en
P2093
P2860
P1476
Thrombopoietin-mediated sustai ...... Rap1-B-Raf-dependent pathways
@en
P2093
Gisselbrecht S
de Gunzburg J
P2860
P304
P356
10.1128/MCB.21.8.2659-2670.2001
P407
P577
2001-04-01T00:00:00Z