Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase.
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Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformationHepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFkappa BN-cadherin mediates neuronal cell survival through Bim down-regulation.Defining the functional domain of programmed cell death 10 through its interactions with phosphatidylinositol-3,4,5-trisphosphate.Ras inhibition induces insulin sensitivity and glucose uptake.The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAFOpposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes.Sensing the environment: a historical perspective on integrin signal transduction.p66(Shc) restrains Ras hyperactivation and suppresses metastatic behavior.Active contractility at E-cadherin junctions and its implications for cell extrusion in cancerAEG-1 promotes anoikis resistance and orientation chemotaxis in hepatocellular carcinoma cells.PDGF beta targeting in cervical cancer cells suggest a fine-tuning of compensatory signalling pathways to sustain tumourigenic stimulationThe Ras-like protein R-Ras2/TC21 is important for proper mammary gland development.MAPK/ERK-dependent translation factor hyperactivation and dysregulated laminin γ2 expression in oral dysplasia and squamous cell carcinoma.p66Shc mediates anoikis through RhoAGrowth factor signalling in prostatic growth: significance in tumour development and therapeutic targeting.Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition.Integration of autophagy and anoikis resistance in solid tumors.RalA regulates vascular endothelial growth factor-C (VEGF-C) synthesis in prostate cancer cells during androgen ablation.Caveolin-1 regulates metastatic behaviors of anoikis resistant lung cancer cells.Contribution of the R-Ras2 GTP-binding protein to primary breast tumorigenesis and late-stage metastatic disease.HOP expression is regulated by p53 and RAS and characteristic of a cancer gene signature.Acquisition of anoikis resistance through CD147 upregulation: A new mechanism underlying metastasis of hepatocellular carcinoma cells.Regulation of Hippo signaling by EGFR-MAPK signaling through Ajuba family proteins.JNK-mediated phosphorylation of paxillin in adhesion assembly and tension-induced cell death by the adenovirus death factor E4orf4.Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells.Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.p27Kip1 modulates cell migration through the regulation of RhoA activation.Mechanotransduction and anoikis: death and the homeless cellTumour-suppression function of KLF12 through regulation of anoikis.Inhibition of Ras oncogenic activity by Ras protooncogenes.Restoration of sensitivity to anoikis in Ras-transformed rat intestinal epithelial cells by a Ras inhibitor.Oncogenic Ras inhibits anoikis of intestinal epithelial cells by preventing the release of a mitochondrial pro-apoptotic protein Omi/HtrA2 into the cytoplasm.Acquisition of anoikis resistance promotes alterations in the Ras/ERK and PI3K/Akt signaling pathways and matrix remodeling in endothelial cells.
P2860
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P2860
Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase.
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Oncogenic Ras blocks anoikis b ...... phosphatidylinositol 3-kinase.
@ast
Oncogenic Ras blocks anoikis b ...... phosphatidylinositol 3-kinase.
@en
type
label
Oncogenic Ras blocks anoikis b ...... phosphatidylinositol 3-kinase.
@ast
Oncogenic Ras blocks anoikis b ...... phosphatidylinositol 3-kinase.
@en
prefLabel
Oncogenic Ras blocks anoikis b ...... phosphatidylinositol 3-kinase.
@ast
Oncogenic Ras blocks anoikis b ...... phosphatidylinositol 3-kinase.
@en
P2093
P2860
P1476
Oncogenic Ras blocks anoikis b ...... phosphatidylinositol 3-kinase.
@en
P2093
P2860
P304
P356
10.1128/MCB.21.16.5488-5499.2001
P407
P577
2001-08-01T00:00:00Z