Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition.
about
The oral HDAC inhibitor pracinostat (SB939) is efficacious and synergistic with the JAK2 inhibitor pacritinib (SB1518) in preclinical models of AML.Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras.Inhibition of PTP1B disrupts cell-cell adhesion and induces anoikis in breast epithelial cells
P2860
Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Romidepsin inhibits Ras-depend ...... y of Ras signaling inhibition.
@en
Romidepsin inhibits Ras-depend ...... y of Ras signaling inhibition.
@nl
type
label
Romidepsin inhibits Ras-depend ...... y of Ras signaling inhibition.
@en
Romidepsin inhibits Ras-depend ...... y of Ras signaling inhibition.
@nl
prefLabel
Romidepsin inhibits Ras-depend ...... y of Ras signaling inhibition.
@en
Romidepsin inhibits Ras-depend ...... y of Ras signaling inhibition.
@nl
P2093
P2860
P356
P1476
Romidepsin inhibits Ras-depend ...... y of Ras signaling inhibition.
@en
P2093
Channing J Der
Jean Nichols
Kevin D Healy
P2860
P356
10.1186/1750-2187-4-5
P577
2009-08-16T00:00:00Z