Matrix metalloproteinase expression levels suggest distinct enzyme roles during lumbar disc herniation and degeneration. - Wikidata - wikimedia - TriplyDB

Matrix metalloproteinase expression levels suggest distinct enzyme roles during lumbar disc herniation and degeneration.

Matrix metalloproteinase expression levels suggest distinct enzyme roles during lumbar disc herniation and degeneration.

http://www.wikidata.org/entity/Q33972129

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Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration Role of cytokines in intervertebral disc degeneration: pain and disc content Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration Developments in intervertebral disc disease research: pathophysiology, mechanobiology, and therapeutics Investigation of the relationship between chromobox homolog 8 and nucleus pulposus cells degeneration in rat intervertebral disc A novel catechol-O-methyltransferase variant associated with human disc degeneration.Matrix Degradative Enzymes and Their Inhibitors during Annular Inflammation: Initial Step of Symptomatic Intervertebral Disc Degeneration.Role of vitamin D3 in treatment of lumbar disc herniation--pain and sensory aspects: study protocol for a randomized controlled trial.Transcript levels of major MMPs and ADAMTS-4 in relation to the clinicopathological profile of patients with lumbar disc herniation.Imbalanced protein expression patterns of anabolic, catabolic, anti-catabolic and inflammatory cytokines in degenerative cervical disc cells: new indications for gene therapeutic treatments of cervical disc diseases Piperine mediates LPS induced inflammatory and catabolic effects in rat intervertebral disc.Photobiomodulation on human annulus fibrosus cells during the intervertebral disk degeneration: extracellular matrix-modifying enzymes.Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration.Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration Serum levels of the proinflammatory cytokine interleukin-6 vary based on diagnoses in individuals with lumbar intervertebral disc diseases.Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration Lentivirus-mediated TGF-β3, CTGF and TIMP1 gene transduction as a gene therapy for intervertebral disc degeneration in an in vivo rabbit model.Cordycepin inhibits LPS-induced inflammatory and matrix degradation in the intervertebral disc.Cells from degenerative intervertebral discs demonstrate unfavorable responses to mechanical and inflammatory stimuli: a pilot study.Chondroadherin fragmentation mediated by the protease HTRA1 distinguishes human intervertebral disc degeneration from normal aging.The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration A combinatorial relative mass value evaluation of endogenous bioactive proteins in three-dimensional cultured nucleus pulposus cells of herniated intervertebral discs: identification of potential target proteins for gene therapeutic approaches.Inflammatory mediators in intervertebral disk degeneration and discogenic pain.Effects of secreted factors in culture medium of annulus fibrosus cells on microvascular endothelial cells: elucidating the possible pathomechanisms of matrix degradation and nerve in-growth in disc degeneration.Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways.The Role of Hypoxia in Angiogenesis and Extracellular Matrix Regulation of Intervertebral Disc Cells During Inflammatory Reactions.Senescent intervertebral disc cells exhibit perturbed matrix homeostasis phenotype.Human nucleus pulposus intervertebral disc cells becoming senescent using different treatments exhibit a similar transcriptional profile of catabolic and inflammatory genes.An organ culture system to model early degenerative changes of the intervertebral disc.[In situ analysis of pathomechanisms of human intervertebral disc degeneration].MicroRNA-125b-1-3p mediates intervertebral disc degeneration in rats by targeting teashirt zinc finger homeobox 3.Expression of serglycin in human disc is increased in degenerated discs and up-regulated in vitro by exposure to IL-1ß or TNF-α.Hyaluronan oligosaccharides stimulate matrix metalloproteinase and anabolic gene expression in vitro by intervertebral disc cells and annular repair in vivo.Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.Expression of matrix metalloproteinases is positively related to the severity of disc degeneration and growing age in the East Asian lumbar disc herniation patients.TGF-β1 antagonizes TNF-α induced up-regulation of matrix metalloproteinase 3 in nucleus pulposus cells: role of the ERK1/2 pathway.Modified house-keeping gene expression in a rat tail compression loading-induced disc degeneration model.A rat tail temporary static compression model reproduces different stages of intervertebral disc degeneration with decreased notochordal cell phenotype.Link N is cleaved by human annulus fibrosus cells generating a fragment with retained biological activity Photobiomodulation of extracellular matrix enzymes in human nucleus pulposus cells as a potential treatment for intervertebral disk degeneration

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P2860

Matrix metalloproteinase expression levels suggest distinct enzyme roles during lumbar disc herniation and degeneration.

http://www.wikidata.org/entity/Q33972129

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2009 nî lūn-bûn

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2009 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2009 թվականի մայիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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Matrix metalloproteinase expre ...... c herniation and degeneration.

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Matrix metalloproteinase expre ...... c herniation and degeneration.

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Matrix metalloproteinase expre ...... c herniation and degeneration.

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Matrix metalloproteinase expre ...... c herniation and degeneration.

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Matrix metalloproteinase expre ...... c herniation and degeneration.

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Matrix metalloproteinase expre ...... c herniation and degeneration.

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European Spine Journal

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Matrix metalloproteinase expre ...... c herniation and degeneration.

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Christianto Lumenta

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Christoph Weiler

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Norbert Boos

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Norbert Mittermaier

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P2860

Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts. Purification and activation of the precursor and enzymic properties

Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

Structure and function of matrix metalloproteinases and TIMPs

Comparative gene expression profiling of normal and degenerative discs: analysis of a rabbit annular laceration model.

Matrix metalloproteinases in the human intervertebral disc: role in disc degeneration and scoliosis.

Histology and pathology of the human intervertebral disc.

Intervertebral disc degeneration: the role of the mitochondrial pathway in annulus fibrosus cell apoptosis induced by overload.

Matrix metalloproteinases in cancer: comparison of known and novel aspects of their inhibition as a therapeutic approach.

Expression of fibronectin and TGF-beta1 mRNA and protein suggest altered regulation of extracellular matrix in degenerated disc tissue.

2002 SSE Award Competition in Basic Science: expression of major matrix metalloproteinases is associated with intervertebral disc degradation and resorption.

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