Opioid-receptor-heteromer-specific trafficking and pharmacology. - Wikidata - wikimedia - TriplyDB

Opioid-receptor-heteromer-specific trafficking and pharmacology.

Opioid-receptor-heteromer-specific trafficking and pharmacology.

http://www.wikidata.org/entity/Q33978499

about

Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerization The δ opioid receptor agonist SNC80 selectively activates heteromeric μ-δ opioid receptors Basic Pharmacological and Structural Evidence for Class A G-Protein-Coupled Receptor Heteromerization Opioid receptor trafficking and interaction in nociceptors Physiology and pathophysiology of the blood-brain barrier: P-glycoprotein and occludin trafficking as therapeutic targets to optimize central nervous system drug delivery Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors Opioid receptors: toward separation of analgesic from undesirable effects The oligomeric state sets GABA(B) receptor signalling efficacy Label-free integrative pharmacology on-target of opioid ligands at the opioid receptor family Oligomerization of G-protein-coupled receptors: a reality A cell-based, high-throughput homogeneous time-resolved fluorescence assay for the screening of potential κ-opioid receptor agonists.Heterologous regulation of Mu-opioid (MOP) receptor mobility in the membrane of SH-SY5Y cells.Mix and match: heterodimers and opioid tolerance.Opioid bifunctional ligands from morphine and the opioid pharmacophore Dmt-Tic.Heteromers of μ-δ opioid receptors: new pharmacology and novel therapeutic possibilities.Recent advances on the δ opioid receptor: from trafficking to function.In vivo opioid receptor heteromerization: where do we stand?Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking.GRK2 protein-mediated transphosphorylation contributes to loss of function of μ-opioid receptors induced by neuropeptide FF (NPFF2) receptors.Opiate antagonist prevents μ- and δ-opiate receptor dimerization to facilitate ability of agonist to control ethanol-altered natural killer cell functions and mammary tumor growth.Biological Significance of GPCR Heteromerization in the Neuro-Endocrine System A non-synonymous single nucleotide polymorphism in an OPRM1 splice variant is associated with fentanyl-induced emesis in women undergoing minor gynaecological surgery Delta opioid receptor analgesia: recent contributions from pharmacology and molecular approaches.Molecular Pharmacology of δ-Opioid Receptors.Probes for narcotic receptor mediated phenomena. 47. Novel C4a- and N-substituted-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols.Delta opioid receptors in brain function and diseases Peripheral δ-opioid receptors attenuate the exercise pressor reflex Activation of spinal mu- and delta-opioid receptors potently inhibits substance P release induced by peripheral noxious stimuli Role of the mu-opioid receptor in opioid modulation of immune function.GPCR dimers fall apart.Interaction and regulatory functions of μ- and δ-opioid receptors in nociceptive afferent neurons.Grand opening of structure-guided design for novel opioids.The role of δ-opioid receptors in learning and memory underlying the development of addiction.Fluorescent knock-in mice to decipher the physiopathological role of G protein-coupled receptors.Heteromultimerization of cannabinoid CB(1) receptor and orexin OX(1) receptor generates a unique complex in which both protomers are regulated by orexin A.Functional consequences of glucagon-like peptide-1 receptor cross-talk and trafficking.Structural biology: How opioid drugs bind to receptors.NPYFa, A Chimeric Peptide of Met-Enkephalin, and NPFF Induces Tolerance-Free Analgesia.Clinical opioids differentially induce co-internalization of μ- and δ-opioid receptors.Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits.

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Opioid-receptor-heteromer-specific trafficking and pharmacology.

http://www.wikidata.org/entity/Q33978499

description

2009 nî lūn-bûn

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2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Opioid-receptor-heteromer-specific trafficking and pharmacology.

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Opioid-receptor-heteromer-specific trafficking and pharmacology.

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Opioid-receptor-heteromer-specific trafficking and pharmacology.

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Opioid-receptor-heteromer-specific trafficking and pharmacology.

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Opioid-receptor-heteromer-specific trafficking and pharmacology.

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J.COPH.2009.09.007

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Current Opinion in Pharmacology

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Opioid-receptor-heteromer-specific trafficking and pharmacology.

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Jennifer L Whistler

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Maria Waldhoer

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Richard M van Rijn

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P2860

A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers.

G-protein-coupled receptor heterodimerization modulates receptor function

Building a new conceptual framework for receptor heteromers

Characterization and visualization of rat and guinea pig brain kappa opioid receptors: evidence for kappa 1 and kappa 2 opioid receptors

Heterodimerization of mu and delta opioid receptors: A role in opiate synergy

Modulation of postendocytic sorting of G protein-coupled receptors

The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence

Morphine desensitization, internalization, and down-regulation of the mu opioid receptor is facilitated by serotonin 5-hydroxytryptamine2A receptor coactivation

Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation

Pharmacological Properties of Bivalent Ligands Containing Butorphan Linked to Nalbuphine, Naltrexone, and Naloxone at μ, δ, and κ Opioid Receptors

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