Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action.
about
Novel approach to mapping of resistance mutations in whole genomes by using restriction enzyme modulation of transformation efficiencyAn ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to avilamycin in the producer organism Streptomyces viridochromogenes Tü57.Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage.Differences in antibiotic resistance patterns of Enterococcus faecalis and Enterococcus faecium strains isolated from farm and pet animals.Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA bindingAntimicrobial growth promoters used in animal feed: effects of less well known antibiotics on gram-positive bacteria.Differential effects of thiopeptide and orthosomycin antibiotics on translational GTPases.A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit.Vancomycin resistance: occurrence, mechanisms and strategies to combat it.Bactobolin resistance is conferred by mutations in the L2 ribosomal protein.Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.Bioactive oligosaccharide natural products.Alterations in MurM, a cell wall muropeptide branching enzyme, increase high-level penicillin and cephalosporin resistance in Streptococcus pneumoniae.Interaction of avilamycin with ribosomes and resistance caused by mutations in 23S rRNA.Evernimicin binds exclusively to the 50S ribosomal subunit and inhibits translation in cell-free systems derived from both gram-positive and gram-negative bacteria.Effects of mutations in ribosomal protein L16 on susceptibility and accumulation of evernimicin.Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants.Mutations in ribosomal protein L16 and in 23S rRNA in Enterococcus strains for which evernimicin MICs differEmtA, a rRNA methyltransferase conferring high-level evernimicin resistance.
P2860
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P2860
Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action.
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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name
Mutations in ribosomal protein ...... tions for mechanism of action.
@ast
Mutations in ribosomal protein ...... tions for mechanism of action.
@en
type
label
Mutations in ribosomal protein ...... tions for mechanism of action.
@ast
Mutations in ribosomal protein ...... tions for mechanism of action.
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prefLabel
Mutations in ribosomal protein ...... tions for mechanism of action.
@ast
Mutations in ribosomal protein ...... tions for mechanism of action.
@en
P2093
P2860
P1476
Mutations in ribosomal protein ...... ations for mechanism of action
@en
P2093
P2860
P304
P356
10.1128/AAC.44.3.732-738.2000
P407
P50
P577
2000-03-01T00:00:00Z