Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants. - Wikidata - wikimedia - TriplyDB

Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants.

Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants.

http://www.wikidata.org/entity/Q39537223

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Deleterious mutations in small subunit ribosomal RNA identify functional sites and potential targets for antibiotics.Combined antimicrobial resistance in Enterococcus faecium isolated from chickens.Heterogeneous macrolide resistance and gene conversion in the pneumococcus Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding Antimicrobial growth promoters used in animal feed: effects of less well known antibiotics on gram-positive bacteria.Differential effects of thiopeptide and orthosomycin antibiotics on translational GTPases.A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit.Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain.Vancomycin resistance: occurrence, mechanisms and strategies to combat it.Public health evolutionary biology of antimicrobial resistance: priorities for intervention Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.Interaction of avilamycin with ribosomes and resistance caused by mutations in 23S rRNA.Effects of mutations in ribosomal protein L16 on susceptibility and accumulation of evernimicin.Mutations in ribosomal protein L16 and in 23S rRNA in Enterococcus strains for which evernimicin MICs differ Recombination proficiency influences frequency and locus of mutational resistance to linezolid in Enterococcus faecalis Influence of recombination on development of mutational resistance to linezolid in Enterococcus faecalis JH2-2.EmtA, a rRNA methyltransferase conferring high-level evernimicin resistance.Potential new antibiotic sites in the ribosome revealed by deleterious mutations in RNA of the large ribosomal subunit.

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P2860

Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants.

http://www.wikidata.org/entity/Q39537223

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2000 nî lūn-bûn

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Evernimicin (SCH27899) inhibit ...... of 23S ribosomal DNA mutants.

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Evernimicin (SCH27899) inhibit ...... of 23S ribosomal DNA mutants.

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AAC.44.11.3101-3106.2000

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Antimicrobial Agents and Chemotherapy

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Evernimicin (SCH27899) inhibit ...... s of 23S ribosomal DNA mutants

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C Mendrick

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D Loebenberg

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K P Klugman

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P V Adrian

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R S Hare

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T A Black

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P2860

An unmodified heptadecapeptide pheromone induces competence for genetic transformation in Streptococcus pneumoniae

Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action.

Construction and initial characterization of Escherichia coli strains with few or no intact chromosomal rRNA operons.

Ribosomal protein gene sequence changes in erythromycin-resistant mutants of Escherichia coli.

Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori.

Erythromycin resistance due to a mutation in a ribosomal RNA operon of Escherichia coli.

Introducing mutations into the single-copy chromosomal 23S rRNA gene of the archaeon Halobacterium halobium by using an rRNA operon-based transformation system

"Megaprimer" method of PCR-based mutagenesis: the concentration of megaprimer is a critical factor.

Ribosomal protein L16 binds to the 3'-end of transfer RNA.

RecA-Mediated gene conversion and aminoglycoside resistance in strains heterozygous for rRNA.

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