Dendrimers, a new class of candidate topical microbicides with activity against herpes simplex virus infection
about
Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issuesToxicological considerations when creating nanoparticle-based drugs and drug delivery systemsPeptidomimetic Star Polymers for Targeting Biological Ion ChannelsSPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humansStructure activity relationship of dendrimer microbicides with dual action antiviral activityDendrimeric β-cyclodextrin/Gd(III) chelate supramolecular host-guest adducts as high-relaxivity MRI probes.Antibacterial activities of poly(amidoamine) dendrimers terminated with amino and poly(ethylene glycol) groupsAntibacterial activity and cytotoxicity of PEGylated poly(amidoamine) dendrimers.Identification of a dendrimeric heparan sulfate-binding peptide that inhibits infectivity of genital types of human papillomaviruses.Efficacy and toxicity of zinc salts as candidate topical microbicides against vaginal herpes simplex virus type 2 infection.Recurrent vaginal shedding of herpes simplex type 2 virus in the mouse and effects of antiviral therapy.Inhibition of bacterial growth and intramniotic infection in a guinea pig model of chorioamnionitis using PAMAM dendrimers.Evaluations of unformulated and formulated dendrimer-based microbicide candidates in mouse and guinea pig models of genital herpesPreclinical safety and efficacy assessments of dendrimer-based (SPL7013) microbicide gel formulations in a nonhuman primate modelPhase 1 randomized trial of the vaginal safety and acceptability of SPL7013 gel (VivaGel) in sexually active young women (MTN-004)Engineered commensal bacteria as delivery systems of anti-infective mucosal protectants.Preclinical testing of candidate topical microbicides for anti-human immunodeficiency virus type 1 activity and tissue toxicity in a human cervical explant culture.Effect of topical microbicides on infectious human immunodeficiency virus type 1 binding to epithelial cellsPeptide- and saccharide-conjugated dendrimers for targeted drug delivery: a concise review.Magnetic resonance nanoparticles for cardiovascular molecular imaging and therapy.Injectable PAMAM dendrimer-PEG hydrogels for the treatment of genital infections: formulation and in vitro and in vivo evaluationDendrimers functionalized with membrane-interacting peptides for viral inhibition.Antiviral mechanism of polyanionic carbosilane dendrimers against HIV-1.Amphipathic DNA polymers exhibit antiherpetic activity in vitro and in vivo.Prevention of vaginal and rectal herpes simplex virus type 2 transmission in mice: mechanism of antiviral action.Past and future evolution in colloidal drug delivery systems.Potent adjuvant activity of cationic liposome-DNA complexes for genital herpes vaccinesDendrimers for enhanced drug solubilization.Novel approaches in fighting herpes simplex virus infectionsSurface-engineered dendrimers: a solution for toxicity issues.Dendrimeric nanoarchitectures mediated transdermal and oral delivery of bioactivesIn vitro comparison of topical microbicides for prevention of human immunodeficiency virus type 1 transmissionDendrimers as therapeutic agents: a systematic review.Understanding specific and nonspecific toxicities: a requirement for the development of dendrimer-based pharmaceuticals.Peptide inhibitors against herpes simplex virus infections.Dendrimers - from organic synthesis to pharmaceutical applications: an update.Mechanistic Studies of Viral Entry: An Overview of Dendrimer-Based Microbicides As Entry Inhibitors Against Both HIV and HSV-2 Overlapped Infections.Inhibition of herpes simplex virus type 1 and type 2 infections by peptide-derivatized dendrimers.Hyperbranched molecular structures with potential antiviral activity: derivatives of 5,6-dihydroxyindole-2-carboxylic Acid.Solid-state NMR reveals the hydrophobic-core location of poly(amidoamine) dendrimers in biomembranes.
P2860
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P2860
Dendrimers, a new class of candidate topical microbicides with activity against herpes simplex virus infection
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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name
Dendrimers, a new class of can ...... herpes simplex virus infection
@ast
Dendrimers, a new class of can ...... herpes simplex virus infection
@en
type
label
Dendrimers, a new class of can ...... herpes simplex virus infection
@ast
Dendrimers, a new class of can ...... herpes simplex virus infection
@en
prefLabel
Dendrimers, a new class of can ...... herpes simplex virus infection
@ast
Dendrimers, a new class of can ...... herpes simplex virus infection
@en
P2093
P2860
P1476
Dendrimers, a new class of can ...... herpes simplex virus infection
@en
P2093
B Matthews
D I Bernstein
L R Stanberry
P2860
P304
P356
10.1128/AAC.44.9.2471-2474.2000
P407
P577
2000-09-01T00:00:00Z