Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways. - Wikidata - wikimedia - TriplyDB

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways.

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways.

http://www.wikidata.org/entity/Q33985888

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Identification of regulators of chaperone-mediated autophagy Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP Strategies for treatment in Alexander disease Alexander disease Dysfunctions of neuronal and glial intermediate filaments in disease S-Nitrosylation of Bcl-2 Negatively Affects Autophagy in Lung Epithelial Cells Genetic ablation of Nrf2/antioxidant response pathway in Alexander disease mice reduces hippocampal gliosis but does not impact survival Antioxidant Treatment and Induction of Autophagy Cooperate to Reduce Desmin Aggregation in a Cellular Model of Desminopathy The origin of Rosenthal fibers and their contributions to astrocyte pathology in Alexander disease CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy BECN1-dependent CASP2 incomplete autophagy induction by binding to rabies virus phosphoprotein.The absence of interleukin-6 enhanced arsenite-induced renal injury by promoting autophagy of tubular epithelial cells with aberrant extracellular signal-regulated kinase activation.Astrocytic TDP-43 pathology in Alexander disease Hydrogen sulfide ameliorates ischemia/reperfusion-induced hepatitis by inhibiting apoptosis and autophagy pathways.Oligomers of mutant glial fibrillary acidic protein (GFAP) Inhibit the proteasome system in alexander disease astrocytes, and the small heat shock protein alphaB-crystallin reverses the inhibition.Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP.SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition.New insights into the function of Atg9.Alexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrease cell viability.Hydrogen sulfide, a potential novel drug, attenuates concanavalin A-induced hepatitis.Crotoxin induces apoptosis and autophagy in human lung carcinoma cells in vitro via activation of the p38MAPK signaling pathway Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK).Protein misfolding and oxidative stress promote glial-mediated neurodegeneration in an Alexander disease model The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation Protective Macroautophagy Is Involved in Vitamin E Succinate Effects on Human Gastric Carcinoma Cell Line SGC-7901 by Inhibiting mTOR Axis Phosphorylation.Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells.Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease.Neurological diseases as primary gliopathies: a reassessment of neurocentrism Alexander disease mutant glial fibrillary acidic protein compromises glutamate transport in astrocytes Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells, as sustained by NF-κB and JNK inhibition.CSF and Blood Levels of GFAP in Alexander Disease Third target of rapamycin complex negatively regulates development of quiescence in Trypanosoma brucei.Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.Protein changes in immunodepleted cerebrospinal fluid from a transgenic mouse model of Alexander disease detected using mass spectrometry GFAP expression as an indicator of disease severity in mouse models of Alexander disease.Oyaksungisan, a Traditional Herbal Formula, Inhibits Cell Proliferation by Induction of Autophagy via JNK Activation in Human Colon Cancer Cells Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander disease Composition of Rosenthal Fibers, the Protein Aggregate Hallmark of Alexander Disease Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis.

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Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways.

http://www.wikidata.org/entity/Q33985888

description

2008 nî lūn-bûn

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2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի փետրվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Autophagy induced by Alexander ...... K and mTOR signaling pathways.

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Autophagy induced by Alexander ...... K and mTOR signaling pathways.

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type

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Autophagy induced by Alexander ...... K and mTOR signaling pathways.

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Autophagy induced by Alexander ...... K and mTOR signaling pathways.

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Autophagy induced by Alexander ...... K and mTOR signaling pathways.

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Autophagy induced by Alexander ...... K and mTOR signaling pathways.

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Human Molecular Genetics

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Autophagy induced by Alexander ...... K and mTOR signaling pathways.

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Albee Messing

http://www.w3.org/2001/XMLSchema#string

David L Sulzer

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Guomei Tang

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James E Goldman

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Tracy Hagemann

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Woosung Cho

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Zhenyu Yue

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Zsolt Talloczy

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P2860

Mechanism of activation of protein kinase B by insulin and IGF-1

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

The roles of intracellular protein-degradation pathways in neurodegeneration

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10.1093/HMG/DDN042

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11

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17

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18276609

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