FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells
about
Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancerNovel agents for advanced pancreatic cancerNetwork-based analysis of multivariate gene expression data.Targeted therapies for pancreatic adenocarcinoma: Where do we stand, how far can we go?Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivoInhibition of focal adhesion kinase and src increases detachment and apoptosis in human neuroblastoma cell linesInhibition of focal adhesion kinase decreases tumor growth in human neuroblastomaPancreatic cancer: molecular pathogenesis and new therapeutic targets.IGF-IR promotes prostate cancer growth by stabilizing α5β1 integrin protein levelsA novel strategy to inhibit FAK and IGF-1R decreases growth of pancreatic cancer xenograftsIGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration.Inhibition of FAK and VEGFR-3 binding decreases tumorigenicity in neuroblastoma.Resveratrol suppresses human colon cancer cell proliferation and induces apoptosis via targeting the pentose phosphate and the talin-FAK signaling pathways-A proteomic approach.Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival.Current knowledge on pancreatic cancer.Molecular targeted approaches for treatment of pancreatic cancer.Disruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth.Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide.A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer.Regulation of Ligand and Shear Stress-induced Insulin-like Growth Factor 1 (IGF1) Signaling by the Integrin Pathway.Pancreatic adenocarcinoma: new strategies for successInhibition of the focal adhesion kinase and vascular endothelial growth factor receptor-3 interaction leads to decreased survival in human neuroblastoma cell lines.Identification of Insulin-Like Growth Factor-I Receptor (IGF-IR) Gene Promoter-Binding Proteins in Estrogen Receptor (ER)-Positive and ER-Depleted Breast Cancer Cells.Targeting of the protein interaction site between FAK and IGF-1R.New treatment options for advanced pancreatic cancer.Monoclonal antibodies in the treatment of pancreatic cancer.Disease evidence for IGFBP-2 as a key player in prostate cancer progression and development of osteosclerotic lesions.Molecular changes in pancreatic cancer.Focal adhesion kinase and p53 signal transduction pathways in cancer.The dual kinase complex FAK-Src as a promising therapeutic target in cancerFocal adhesion kinase as a cancer therapy target.Emerging pathways and future targets for the molecular therapy of pancreatic cancer.Role of ion transport in control of apoptotic cell death.Targeting FAK in human cancer: from finding to first clinical trials.Focal adhesion kinase inhibitors in the treatment of metastatic cancer: a patent review.Decoding the anticancer activity of VO-clioquinol compound: the mechanism of action and cell death pathways in human osteosarcoma cells.Deciphering the effect of an oxovanadium(iv) complex with the flavonoid chrysin (VOChrys) on intracellular cell signalling pathways in an osteosarcoma cell line.Molecular Targeting of Integrins and Integrin-Associated Signaling Networks in Radiation Oncology.A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cells.An activity-based probe reveals dynamic protein-protein interactions mediating IGF-1R transactivation by the GABA(B) receptor.
P2860
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P2860
FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells
@ast
FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells
@en
type
label
FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells
@ast
FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells
@en
prefLabel
FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells
@ast
FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells
@en
P2093
P2860
P356
P1433
P1476
FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells
@en
P2093
David A Bloom
Elena V Kurenova
Steven N Hochwald
Vita M Golubovskaya
Weiguo Liu
William G Cance
P2860
P304
P356
10.1093/CARCIN/BGN026
P407
P577
2008-02-07T00:00:00Z