FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells - Wikidata - wikimedia - TriplyDB

FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells

FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells

http://www.wikidata.org/entity/Q33986318

about

Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer Novel agents for advanced pancreatic cancer Network-based analysis of multivariate gene expression data.Targeted therapies for pancreatic adenocarcinoma: Where do we stand, how far can we go?Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo Inhibition of focal adhesion kinase and src increases detachment and apoptosis in human neuroblastoma cell lines Inhibition of focal adhesion kinase decreases tumor growth in human neuroblastoma Pancreatic cancer: molecular pathogenesis and new therapeutic targets.IGF-IR promotes prostate cancer growth by stabilizing α5β1 integrin protein levels A novel strategy to inhibit FAK and IGF-1R decreases growth of pancreatic cancer xenografts IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration.Inhibition of FAK and VEGFR-3 binding decreases tumorigenicity in neuroblastoma.Resveratrol suppresses human colon cancer cell proliferation and induces apoptosis via targeting the pentose phosphate and the talin-FAK signaling pathways-A proteomic approach.Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival.Current knowledge on pancreatic cancer.Molecular targeted approaches for treatment of pancreatic cancer.Disruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth.Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide.A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer.Regulation of Ligand and Shear Stress-induced Insulin-like Growth Factor 1 (IGF1) Signaling by the Integrin Pathway.Pancreatic adenocarcinoma: new strategies for success Inhibition of the focal adhesion kinase and vascular endothelial growth factor receptor-3 interaction leads to decreased survival in human neuroblastoma cell lines.Identification of Insulin-Like Growth Factor-I Receptor (IGF-IR) Gene Promoter-Binding Proteins in Estrogen Receptor (ER)-Positive and ER-Depleted Breast Cancer Cells.Targeting of the protein interaction site between FAK and IGF-1R.New treatment options for advanced pancreatic cancer.Monoclonal antibodies in the treatment of pancreatic cancer.Disease evidence for IGFBP-2 as a key player in prostate cancer progression and development of osteosclerotic lesions.Molecular changes in pancreatic cancer.Focal adhesion kinase and p53 signal transduction pathways in cancer.The dual kinase complex FAK-Src as a promising therapeutic target in cancer Focal adhesion kinase as a cancer therapy target.Emerging pathways and future targets for the molecular therapy of pancreatic cancer.Role of ion transport in control of apoptotic cell death.Targeting FAK in human cancer: from finding to first clinical trials.Focal adhesion kinase inhibitors in the treatment of metastatic cancer: a patent review.Decoding the anticancer activity of VO-clioquinol compound: the mechanism of action and cell death pathways in human osteosarcoma cells.Deciphering the effect of an oxovanadium(iv) complex with the flavonoid chrysin (VOChrys) on intracellular cell signalling pathways in an osteosarcoma cell line.Molecular Targeting of Integrins and Integrin-Associated Signaling Networks in Radiation Oncology.A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cells.An activity-based probe reveals dynamic protein-protein interactions mediating IGF-1R transactivation by the GABA(B) receptor.

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P2860

FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells

http://www.wikidata.org/entity/Q33986318

description

2008 nî lūn-bûn

@nan

2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells

@ast

FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells

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type

label

FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells

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FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells

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prefLabel

FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells

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FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells

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FAK and IGF-IR interact to pro ...... ancreatic adenocarcinoma cells

@en

P2093

David A Bloom

http://www.w3.org/2001/XMLSchema#string

Elena V Kurenova

http://www.w3.org/2001/XMLSchema#string

Steven N Hochwald

http://www.w3.org/2001/XMLSchema#string

Vita M Golubovskaya

http://www.w3.org/2001/XMLSchema#string

Weiguo Liu

http://www.w3.org/2001/XMLSchema#string

William G Cance

http://www.w3.org/2001/XMLSchema#string

P2860

C-terminal Src kinase associates with ligand-stimulated insulin-like growth factor-I receptor

FAK integrates growth-factor and integrin signals to promote cell migration

Altered expression of insulin-like growth factor II receptor in human pancreatic cancer

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

Control of adhesion-dependent cell survival by focal adhesion kinase

Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells.

Blockade of IGF-1 receptor tyrosine kinase has antineoplastic effects in hepatocellular carcinoma cells.

Insulin-like growth factor I overexpression in human pancreatic cancer: evidence for autocrine and paracrine roles.

Control of cell survival by IGF signaling pathways.

Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer

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1096-1107

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scholarly article

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10.1093/CARCIN/BGN026

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6

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29

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2008-02-07T00:00:00Z

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5587751

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18263593

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2902396

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