Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains.
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Structure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog FoldNext-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungiCharacterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreusInsights into the biosynthesis of 12-membered resorcylic acid lactones from heterologous production in Saccharomyces cerevisiae.Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthasesDiversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases.New insights into the formation of fungal aromatic polyketides.Bioinformatical analysis of the sequences, structures and functions of fungal polyketide synthase product template domains.Starter unit flexibility for engineered product synthesis by the nonreducing polyketide synthase PksASnPKS19 Encodes the Polyketide Synthase for Alternariol Mycotoxin Biosynthesis in the Wheat Pathogen Parastagonospora nodorumIlluminating the diversity of aromatic polyketide synthases in Aspergillus nidulansPhylogenomic and domain analysis of iterative polyketide synthases in Aspergillus speciesEvolution of Chemical Diversity in a Group of Non-Reduced Polyketide Gene Clusters: Using Phylogenetics to Inform the Search for Novel Fungal Natural Products.Characterization of a fungal thioesterase having Claisen cyclase and deacetylase activities in melanin biosynthesis.Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters in Aspergillus fumigatus.Genomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM)Active site comparisons and catalytic mechanisms of the hot dog superfamily.Rational reprogramming of fungal polyketide first-ring cyclizationThioesterase domains of fungal nonreducing polyketide synthases act as decision gates during combinatorial biosynthesis.Structural analysis of protein-protein interactions in type I polyketide synthasesThree New Non-reducing Polyketide Synthase Genes from the Lichen-Forming Fungus Usnea longissima.A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases.Synthetic biological approaches to natural product biosynthesis.Monascus secondary metabolites: production and biological activity.Genetics of Polyketide Metabolism in Aspergillus nidulans.Comparative characterization of fungal anthracenone and naphthacenedione biosynthetic pathways reveals an α-hydroxylation-dependent Claisen-like cyclization catalyzed by a dimanganese thioesterase.Functional genomics-guided discovery of a light-activated phytotoxin in the wheat pathogen Parastagonospora nodorum via pathway activation.Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers.Systematic domain swaps of iterative, nonreducing polyketide synthases provide a mechanistic understanding and rationale for catalytic reprogramming.The Distant Siblings-A Phylogenomic Roadmap Illuminates the Origins of Extant Diversity in Fungal Aromatic Polyketide Biosynthesis.Navigating the fungal polyketide chemical space: from genes to molecules.Phenalenone Polyketide Cyclization Catalyzed by Fungal Polyketide Synthase and Flavin-Dependent Monooxygenase.Complexity generation in fungal polyketide biosynthesis: a spirocycle-forming P450 in the concise pathway to the antifungal drug griseofulvin.Combinatorial domain swaps provide insights into the rules of fungal polyketide synthase programming and the rational synthesis of non-native aromatic products.Biosynthesis of fusarubins accounts for pigmentation of Fusarium fujikuroi perithecia.Phylogenetic Studies, Gene Cluster Analysis, and Enzymatic Reaction Support Anthrahydroquinone Reduction as the Physiological Function of Fungal 17β-Hydroxysteroid Dehydrogenase.Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans
P2860
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P2860
Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Classification, prediction, an ...... hase product template domains.
@ast
Classification, prediction, an ...... hase product template domains.
@en
Classification, prediction, an ...... hase product template domains.
@nl
type
label
Classification, prediction, an ...... hase product template domains.
@ast
Classification, prediction, an ...... hase product template domains.
@en
Classification, prediction, an ...... hase product template domains.
@nl
prefLabel
Classification, prediction, an ...... hase product template domains.
@ast
Classification, prediction, an ...... hase product template domains.
@en
Classification, prediction, an ...... hase product template domains.
@nl
P2093
P2860
P356
P1476
Classification, prediction, an ...... hase product template domains.
@en
P2093
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P2860
P304
22764-22773
P356
10.1074/JBC.M110.128504
P407
P577
2010-05-17T00:00:00Z