Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha - Wikidata - wikimedia - TriplyDB

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

http://www.wikidata.org/entity/Q34012425

about

Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action Insulin receptor signaling in normal and insulin-resistant states Combined dabrafenib and trametinib treatment in a case of chemotherapy-refractory extrahepatic BRAF V600E mutant cholangiocarcinoma: dramatic clinical and radiological response with a confusing synchronic new liver lesion Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle Difference in gene expression of macrophage between normal spleen and portal hypertensive spleen identified by cDNA microarray.The emerging genetic architecture of type 2 diabetes Phosphatidylinositol 3-kinase p85alpha regulatory subunit gene PIK3R1 haplotype is associated with body fat and serum leptin in a female twin population High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes.PIK3R1Met326Ile germline mutation correlates with cysteine-rich protein 61 expression and poor prognosis in glioblastoma.High-throughput screening identified inherited genetic variations in the EGFR pathway contributing to skin toxicity of EGFR inhibitors.Functional polymorphisms in cancer.Association analysis of the variant in the regulatory subunit of phosphoinositide 3-kinase (p85alpha) with Type 2 diabetes mellitus and hypertension in the Chinese Han population.Functional germline variants as potential co-oncogenes.Linkage and radiation hybrid mapping of the porcine PIK3R1 gene to chromosome 16.Single nucleotide polymorphisms within functional regions of genes implicated in insulin action and association with the insulin resistant phenotype.

P2860

Q24803901-C271F08E-A21D-4F47-8BFE-71B491B6972A Q26823171-E4F98CD2-4910-4321-BC46-665807428258 Q33593231-F829C889-33F3-410D-92A8-8B0606C38C6A Q33750663-AFA32394-3CAD-4D7F-8D8F-B88717A77EE8 Q34233071-23AD147E-4CC9-4F1D-A73B-A8734C1A0554 Q34712198-83158E4A-8769-4299-A8B6-788CD07423D2 Q35112931-0C0CA278-D962-430B-8BD4-41AAACA15D3A Q35275603-3974A7DB-4178-4C59-9587-A69BF2063EDE Q36477469-DF6C079D-48DD-4B00-B3B3-9669E0745428 Q41286737-3BA6986A-4E2D-47CE-B7B6-43CE15B7D299 Q41289945-85E6D60D-2359-48F0-98AD-F8A3EFD35DF0 Q42654692-270234F2-79EC-4CDF-8BF0-D07911B819CC Q46504544-9713CA82-F2D8-49B9-A862-7AB39CA7FEC5 Q47159094-4689E51E-B413-48C1-8649-64AE7D512F9A Q48235925-4D75A3A6-E42C-4387-94DA-7B24785C1C2C Q51385880-24043575-E585-4B06-8D9D-37225518B780

P2860

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

http://www.wikidata.org/entity/Q34012425

description

2002 nî lūn-bûn

@nan

2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年学术文章

@wuu

2002年学术文章

@zh-cn

2002年学术文章

@zh-hans

2002年学术文章

@zh-my

2002年学术文章

@zh-sg

2002年學術文章

@yue

name

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

@ast

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

@en

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

@nl

type

label

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

@ast

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

@en

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

@nl

prefLabel

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

@ast

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

@en

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

@nl

P1433

Q34012425-0F951F1B-B78D-436B-A828-33B4A4ED43C7

P1476

Q34012425-6E1D9BC7-C14A-4C2E-BC30-3C41A8B13937

P2093

Q34012425-2F9D1A05-A304-44FB-A1C6-41E44B7EE043

Q34012425-3DB3A288-3863-4661-AD81-3DEB3CBBBAAF

Q34012425-94E6159C-AA0D-4257-93AA-386D2A59E220

P2860

Q34012425-001B2435-09DA-4F4D-A23D-990DD40B5E63

Q34012425-105DE248-E01A-4CF0-B1C8-FE1DCDD9E76D

Q34012425-1CA580C5-A6A2-4250-A667-7DC72E3FFA6F

Q34012425-2D1B5FD6-509A-437E-88CA-3A6F847D68A3

Q34012425-418DAA07-94CB-474E-9267-AE465E7F1130

Q34012425-43DD3C43-F8CB-4337-A5EB-F92BC2C9996A

Q34012425-4C54AC3C-1D2C-455B-929F-87198140B670

Q34012425-6BD1776B-2817-4C72-B370-742C2CA1CF52

Q34012425-6F647B25-155D-4F4A-92A3-5BB280E1B022

Q34012425-8A6DA150-7A9E-4101-88E5-CE62A5D332A3

P304

Q34012425-FD309FCA-8C9A-4E2D-8B5A-7FA35D54EDBE

P31

Q34012425-E0B92BCD-C1DF-4523-9DC4-8B3DDF9F0523

P356

Q34012425-3BDA39C0-6C0C-4954-8A84-73788008B45D

P407

Q34012425-A851A6B3-646E-4452-BAA6-938421F57261

P433

Q34012425-7ACA5C5C-13EA-49DA-B684-4E4F6F6ED049

P478

Q34012425-E0AA6EED-3471-4C59-9C18-64CCF6E543DE

P50

Q34012425-122121E7-BE5A-4A7F-AB46-722260D863D3

Q34012425-A09CBA6A-92C0-413A-8AB9-4E5F2EA89E5F

Q34012425-A6D3ACA9-74FE-45A7-B160-726E8BF9E575

P577

Q34012425-22B2A0CB-35C2-43D9-8FD6-51FD0531C2EB

P5875

Q34012425-2074E36B-5002-4C62-AEA9-953AAA13D33B

P698

Q34012425-DFB8BF4E-94E3-4A4B-96A7-5DF190497952

P932

Q34012425-3586570F-4B82-4B44-A324-E908C09F173C

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

@en

P2093

Emmanuel Van Obberghen

http://www.w3.org/2001/XMLSchema#string

Katrine Almind

http://www.w3.org/2001/XMLSchema#string

Laurent Delahaye

http://www.w3.org/2001/XMLSchema#string

P2860

Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes

Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules

The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase

Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin.

Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain.

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases.

Tracers to investigate protein and amino acid metabolism in human subjects.

Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.

Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit.

P304

2124-2128

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.042688799

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

99

http://www.w3.org/2001/XMLSchema#string

P50

Oluf Borbye Pedersen

P577

2002-02-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11519278

http://www.w3.org/2001/XMLSchema#string

P698

11842213

http://www.w3.org/2001/XMLSchema#string

P932

122329

http://www.w3.org/2001/XMLSchema#string