The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence.
about
Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesisHypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related DiseasesHistone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and preventionGenetics and epigenetics of aging and longevityHistone demethylase lysine demethylase 5B in development and cancerKdm5/Lid Regulates Chromosome Architecture in Meiotic Prophase I Independently of Its Histone Demethylase ActivityIntegrated analysis of recurrent properties of cancer genes to identify novel driversPhysical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process.Histone methylation and aging: lessons learned from model systems.Mammalian lysine histone demethylase KDM2A regulates E2F1-mediated gene transcription in breast cancer cellsCo-acting gene networks predict TRAIL responsiveness of tumour cells with high accuracy.H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence.The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence.The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoterPharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cellsRecent advances in the ARID family: focusing on roles in human cancer.On the role of retinoblastoma family proteins in the establishment and maintenance of the epigenetic landscape.Regulation of oncogene-induced cell cycle exit and senescence by chromatin modifiersChromatin regulators with tumor suppressor properties and their alterations in human cancers.Emerging targets for combination therapy in melanomas.Epigenetic targets in cancer and aging: dietary and therapeutic interventions.Epigenetic gene regulation by histone demethylases: emerging role in oncogenesis and inflammation.The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers.SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase.Rb1 mRNA expression in developing mouse teethJARID1 Histone Demethylases: Emerging Targets in Cancer.
P2860
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P2860
The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The histone demethylase Jarid1 ...... nes in MEFs during senescence.
@ast
The histone demethylase Jarid1 ...... nes in MEFs during senescence.
@en
The histone demethylase Jarid1b
@nl
type
label
The histone demethylase Jarid1 ...... nes in MEFs during senescence.
@ast
The histone demethylase Jarid1 ...... nes in MEFs during senescence.
@en
The histone demethylase Jarid1b
@nl
prefLabel
The histone demethylase Jarid1 ...... nes in MEFs during senescence.
@ast
The histone demethylase Jarid1 ...... nes in MEFs during senescence.
@en
The histone demethylase Jarid1b
@nl
P2093
P2860
P1433
P1476
The histone demethylase Jarid1 ...... nes in MEFs during senescence.
@en
P2093
Ernst-Jan Geutjes
Jeroen H Nijwening
Roderick L Beijersbergen
P2860
P304
P356
10.1371/JOURNAL.PONE.0025235
P407
P577
2011-09-27T00:00:00Z