The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence. - Wikidata - wikimedia - TriplyDB

The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence.

The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence.

http://www.wikidata.org/entity/Q36114088

about

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy Cell fusion induced by ERVWE1 or measles virus causes cellular senescence HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci Identification of a Low-Frequency Missense Variant in E2F Transcription Factor 7 Associated with Colorectal Cancer Risk In A Chinese Population CtBP2 proteome: Role of CtBP in E2F7-mediated repression and cell proliferation Cellular senescence and protein degradation: breaking down cancer Nucleotide metabolism, oncogene-induced senescence and cancer.The DREAM complex: master coordinator of cell cycle-dependent gene expression.MicroRNA-mediated transformation by the Kaposi's sarcoma-associated herpesvirus Kaposin locus.Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions.Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 rearrangements.MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition.Involvement of atypical transcription factor E2F8 in the polyploidization during mouse and human decidualization.Feedback regulation between atypical E2Fs and APC/CCdh1 coordinates cell cycle progression.Functional repeats (TGYCC)n in the p53-inducible gene 3 (PIG3) promoter and susceptibility to squamous cell carcinoma of the head and neck.Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing.E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation Interaction of E2F7 transcription factor with E2F1 and C-terminal-binding protein (CtBP) provides a mechanism for E2F7-dependent transcription repression Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence.E2f8 mediates tumor suppression in postnatal liver development.Identification of cellular senescence-specific genes by comparative transcriptomics.Evidence for site-specific occupancy of the mitochondrial genome by nuclear transcription factors.Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer.Discrepancy between the effects of morronside on apoptosis in human embryonic lung fibroblast cells and lung cancer A549 cells.Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.A replicative self-renewal model for long-lived plasma cells: questioning irreversible cell cycle exit.Antitumor mechanisms when pRb and p53 are genetically inactivated.E2F Transcription Factors Control the Roller Coaster Ride of Cell Cycle Gene Expression.Tumor-Suppressor Functions of the TP53 Pathway.Metabolic alterations accompanying oncogene-induced senescence.A genomics approach identifies senescence-specific gene expression regulation.Deregulation of RB1 expression by loss of imprinting in human hepatocellular carcinoma.Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation.Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage.Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence.Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress.BTK suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling.Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo.Characterization of the 5'-flanking region of the human TP53 gene and its response to the natural compound, Resveratrol.

P2860

Q27682798-9454EBFE-75E7-4D66-8B67-81C994E6346A Q28301290-36BB8D59-BA8A-4869-8284-96B1E8BD8F6D Q28315115-958F1F48-F5D0-4252-B6A5-E1E2B07DD1D0 Q30399157-B60C4548-4820-420C-A516-A004C0142006 Q33776857-CA881D81-E81F-49A8-BBD5-208B56D6F572 Q33953067-806A4972-5412-4576-8844-1AAAAF6EB74D Q33969333-84EFA12C-C7C8-4AE3-AEE2-41B0FC72A258 Q34356659-B2992AAF-3F08-4223-ADAD-34B4E2E785B8 Q34453771-C754AA82-35AA-40DE-BD8D-949C1B23B2DF Q34483943-0B160FAA-3E36-41F3-81A6-58619792DD93 Q34961997-1B7EA8DF-BF89-4EEC-ABE0-FEECD7E587E8 Q35088118-28C4DCF5-ADCE-4F4E-AD19-26078D4139C1 Q35781547-0AB7F4CA-7690-4763-97D0-FE9352D52EF9 Q36186723-08FA3F5D-D617-4EE6-B67A-A237FD254054 Q36636175-594FB4F7-FC60-4C76-835B-4AB9E6751B3F Q36740684-859939A9-9EE7-45EA-A77C-9341829801BE Q36742729-2F5E35C3-4EC0-40FB-B6F2-0CF869B0CE41 Q37076251-364CA9FC-E078-4F02-896B-759AB6F3AA3D Q37112680-DEEEDCF0-8833-4E29-98FE-92A4BBC3EB26 Q37133206-F1CB4A4C-ABAE-489E-8A5F-C824ABED3A09 Q37137905-2B8CC086-9ACF-4C34-822A-1B7B1EFE9E49 Q37193100-A1B23723-E9CC-4602-A9EE-BF3595D1C3D5 Q37495767-7C427412-98D2-4ACB-90C6-1E79B6EBFA63 Q37644047-A9D72AEF-3087-44F1-B2CB-14E441C6459D Q37652390-66E62859-FA99-4D69-9348-9CAC721E4805 Q37672120-8B887AB9-93D7-4A3A-9683-FF3A534E946E Q38175395-7643A31B-671B-4AED-85B8-897529453978 Q38285170-4C76662D-CBBD-4726-B772-042FED8C89E3 Q38562960-F009A0B9-8543-461B-A837-5467FF075A23 Q38824332-2C144FA3-04AC-4DD0-8950-BB8C38D27795 Q38866719-FE89BFD7-D34B-4B86-B33E-A3364775D955 Q38991326-1F97B2B7-2CAB-4784-9B51-438055467160 Q38994050-113EF12B-D956-4675-A4E3-6A14CB9BB5FB Q38995173-1C32E2CF-B7B7-49FA-B747-9B75FD05FC05 Q39123428-FB9C48C1-FA51-439C-B036-A6343D89E8D9 Q39170489-A8F3F3B4-47B9-42D5-B2BB-32A2DDDCE333 Q40165187-42B363CE-4859-41A4-BD99-F4D616A95C6B Q41344360-863FE0C1-6A7B-4C54-8353-0242EE07A123 Q41892098-9317878C-54F3-470E-BEC0-280F9804E631 Q41908817-F392415A-2418-4DB2-98B1-C9DDDA2B2592

P2860

The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence.

http://www.wikidata.org/entity/Q36114088

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

The atypical E2F family member ...... ys during cellular senescence.

@ast

The atypical E2F family member ...... ys during cellular senescence.

@en

type

label

The atypical E2F family member ...... ys during cellular senescence.

@ast

The atypical E2F family member ...... ys during cellular senescence.

@en

prefLabel

The atypical E2F family member ...... ys during cellular senescence.

@ast

The atypical E2F family member ...... ys during cellular senescence.

@en

P1433

Q36114088-3EBF6906-5BBD-4A18-8D0D-5ABE1F58C767

P1476

Q36114088-127F94C6-EC10-44A0-A11D-6F302D0ED83C

P2093

Q36114088-2B56750C-F5FC-4E9B-A128-40A93DA54DFD

Q36114088-4B5D1D01-4FCB-490E-9D78-1718613380DD

Q36114088-981C1BD9-E7AA-4A0D-B561-7A375770F2F5

Q36114088-A1254BE7-8F02-4131-BA69-4A49BB66EDEA

Q36114088-B754B845-6F0C-4EE2-B158-2D3890268AF6

Q36114088-B8E1B492-8F6A-46B9-96F4-29898EE20113

Q36114088-CF6C1278-D0BD-4D6C-945B-3239C98F1DEA

P2860

Q36114088-01549080-07CC-46AA-9E55-02A3DF423087

Q36114088-025E005A-EDB4-4F62-AD3E-3B2402BA971E

Q36114088-02DE7C1B-4357-43A2-9A71-BF72BAAEB5AD

Q36114088-0AF2A5C7-A3F2-4EDA-9ACC-B660FDEDD17D

Q36114088-0C67ABBD-5B30-4A03-9026-4A225A22F51A

Q36114088-181C0493-634C-4726-9C0A-3D99884B223D

Q36114088-1EB45D8C-A083-4E6E-A530-0C6BBB4CB382

Q36114088-2D1782CD-5688-45C4-8494-13BE5C1D872C

Q36114088-2DD933C1-91DB-4F3F-AFFC-7066D391F763

Q36114088-2FDD7699-D5A8-49D9-BB5E-8FA41BE1BD08

P304

Q36114088-7E09FC5D-98DA-42D1-8383-A0539B303580

P31

Q36114088-A3CA86C7-365E-415D-A153-8BA2E8A274F7

P356

Q36114088-DB4F21B2-2306-4732-A493-083FA9751935

P433

Q36114088-06D20F85-FFC2-4118-A014-EDF20B03E90B

P478

Q36114088-2042C912-9F33-484A-8F7A-AA07D3F573E4

P577

Q36114088-6CD82700-21CD-456C-964C-273D34E995C5

P5875

Q36114088-3FE63573-E7FA-4FC6-94D3-5E210EF826DC

P698

Q36114088-4B7A0117-0F9E-483C-84E9-65B25BCA36D0

P932

Q36114088-7AE5B3CD-034B-45F4-AD3C-E6D4B928B60B

P356

P1433

Genes & Development

P1476

The atypical E2F family member ...... ys during cellular senescence.

@en

P2093

Agustin Chicas

http://www.w3.org/2001/XMLSchema#string

Mila McCurrach

http://www.w3.org/2001/XMLSchema#string

Ozlem Aksoy

http://www.w3.org/2001/XMLSchema#string

Scott W Lowe

http://www.w3.org/2001/XMLSchema#string

Tianying Zeng

http://www.w3.org/2001/XMLSchema#string

Xiaowo Wang

http://www.w3.org/2001/XMLSchema#string

Zhen Zhao

http://www.w3.org/2001/XMLSchema#string

P2860

Model-based analysis of ChIP-Seq (MACS)

E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains

DNA-damage response control of E2F7 and E2F8

Autophagy mediates the mitotic senescence transition

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes

Cluster analysis and display of genome-wide expression patterns

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

P304

1546-1557

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1101/GAD.196238.112

http://www.w3.org/2001/XMLSchema#string

P433

14

http://www.w3.org/2001/XMLSchema#string

P478

26

http://www.w3.org/2001/XMLSchema#string

P577

2012-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

229156997

http://www.w3.org/2001/XMLSchema#string

P698

22802529

http://www.w3.org/2001/XMLSchema#string

P932

3404383

http://www.w3.org/2001/XMLSchema#string