Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma. - Wikidata - wikimedia - TriplyDB

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma.

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma.

http://www.wikidata.org/entity/Q34069375

about

EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma Intratumor heterogeneity: evolution through space and time Single-cell analysis tools for drug discovery and development Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment Insights into Chemoresistance of Prostate Cancer Ligand-Independent EGFR Signaling Evolutionary determinants of cancer Molecular characterizations of glioblastoma, targeted therapy, and clinical results to date Challenges to targeting epidermal growth factor receptor in glioblastoma: escape mechanisms and combinatorial treatment strategies EGFR Amplification and Glioblastoma Stem-Like Cells Tumour heterogeneity and the evolution of polyclonal drug resistance Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered Clonal evolution in hematological malignancies and therapeutic implications A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study.The role of tumor microenvironment in therapeutic resistance Imaging metabolic heterogeneity in cancer Current Therapeutic Advances Targeting EGFR and EGFRvIII in Glioblastoma The somatic genomic landscape of glioblastoma Hypoxia-induced aggressiveness of pancreatic cancer cells is due to increased expression of VEGF, IL-6 and miR-21, which can be attenuated by CDF treatment Lifespan based pharmacokinetic-pharmacodynamic model of tumor growth inhibition by anticancer therapeutics The causes and consequences of genetic heterogeneity in cancer evolution Quantitative Analysis of the Cellular Microenvironment of Glioblastoma to Develop Predictive Statistical Models of Overall Survival.Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling.Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells.Alpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch.miR-219-5p inhibits receptor tyrosine kinase pathway by targeting EGFR in glioblastoma.Spatial Habitat Features Derived from Multiparametric Magnetic Resonance Imaging Data Are Associated with Molecular Subtype and 12-Month Survival Status in Glioblastoma Multiforme.EGFR soluble isoforms and their transcripts are expressed in meningiomas.Frequency of NFKBIA deletions is low in glioblastomas and skewed in glioblastoma neurospheres.An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma.Glioblastoma cellular architectures are predicted through the characterization of two-cell interactions Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma.The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome Multiplicity: an organizing principle for cancers and somatic mutations.EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis.

P2860

Q24338526-695C29FA-C052-470B-97C6-7713781B4855 Q24598678-A8124CA8-66E4-4BE8-A138-00F5D00C07B9 Q26775754-85D513DB-477D-4E9F-A9D1-ADC5A7D41921 Q26783055-E0A5904F-82F5-4700-A77A-64ABF99DE5A0 Q26795589-282D4413-6F95-4085-B759-F474946070A4 Q26797495-C5B68B77-4DA3-4D6A-BF5C-F84CC4E8A657 Q26801710-6C5A512F-6AD4-4301-81F7-BB6C9B30900A Q26822717-D45A9838-CC7B-4F21-89EC-016859325B01 Q26852366-7570F025-054D-4628-AE75-3EC1254A6491 Q26853549-9BD91E39-AA40-441F-9F38-081066FA5A34 Q26866803-2F8677F0-4525-4EE5-8C54-C02498B46D97 Q27013006-1FA762AB-7796-42D1-9591-F6CBC48DA8B8 Q27015045-A9F35246-E04C-4C70-BC9C-6AD8A5B9692D Q27027655-F2A2DEB2-9235-4BB0-B095-55EDE599E0BF Q27324733-B1C72CD8-7992-4405-A4D7-66A97892BC1F Q27853118-9266FB7D-BA7D-47A1-8A60-D6ECD3CBF3F5 Q28069049-DC46BD57-96FD-487C-B5F6-3DEC046CC1D6 Q28076500-DFC3AEBA-3AB2-40E4-AF11-0F181C8F84AB Q28087306-8881AAA4-D121-4D9F-8490-40C0F38EF1CF Q28300185-4A99E811-1FCE-4E6D-BAFF-6A619838A2AE Q28484357-AE4D6EB2-3E76-410E-9B2B-DA120EBBB3DE Q28543966-96E87488-F1D5-42D0-BDE8-9EBBBF57A929 Q29615848-52DBCAF4-38DB-4BAC-9407-9307B5AAE518 Q30275479-6901A06E-FEDA-4F3C-A26A-F7CF7BA4D819 Q30361219-B16FD53F-2E42-4A97-BC4D-18D2C2C06DE4 Q30393905-1ED245CF-2493-4737-85E6-CA1D2B40A395 Q30417011-9EFEFF87-607D-4741-A840-9DB02400BDDF Q30419258-A66A955B-AA15-4DDC-8153-F439BDC6EC6F Q30993492-08E3DB93-164D-447F-B7AB-EBA540C851BE Q31062214-0685F004-3A16-491A-A474-022E848B13F0 Q33643498-0E0835DF-F2F9-43BE-B4AD-D523CF14FB0F Q33665884-F2E5A80E-1DEB-4046-8250-ED0853753371 Q33674388-3D0D7C8A-C985-4033-8A05-C969F575B1A1 Q33725972-984F6E47-E1BA-4BD9-A26F-7BDB9837F0B0 Q33731292-F420A100-D8E3-42ED-8A46-98F52F99D8B5 Q33779029-546D729E-94DD-438B-8012-B315FB250182 Q33913152-1C0D6517-E8D9-4815-A267-E60171EE9C2F Q33945991-591B10C5-4685-4C2B-939B-5B5E62EEFF35 Q34016908-D059CCC6-6AA4-4137-A9C4-336CC3E88E17 Q34117589-90965CDA-00CB-41B0-841D-40501EB378A5

P2860

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma.

http://www.wikidata.org/entity/Q34069375

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Tumor heterogeneity is an acti ...... okine circuit in glioblastoma.

@ast

Tumor heterogeneity is an acti ...... okine circuit in glioblastoma.

@en

Tumor heterogeneity is an acti ...... okine circuit in glioblastoma.

@nl

type

label

Tumor heterogeneity is an acti ...... okine circuit in glioblastoma.

@ast

Tumor heterogeneity is an acti ...... okine circuit in glioblastoma.

@en

Tumor heterogeneity is an acti ...... okine circuit in glioblastoma.

@nl

prefLabel

Tumor heterogeneity is an acti ...... okine circuit in glioblastoma.

@ast

Tumor heterogeneity is an acti ...... okine circuit in glioblastoma.

@en

Tumor heterogeneity is an acti ...... okine circuit in glioblastoma.

@nl

P1433

Q34069375-FCEB0211-6265-49B8-9264-FEF3F7CCBEB7

P1476

Q34069375-9DDC2778-8D6F-4D02-A167-0007CAEDC683

P2093

Q34069375-06E93C64-9AE6-499C-BE50-9D727D4071A9

Q34069375-08581FD7-DBAF-40DC-A175-CC42222CDD18

Q34069375-089DD883-E099-4309-B25B-A6EA4FDF4418

Q34069375-09BC6972-F9DB-4AF6-AE5E-B92D41BB0E0C

Q34069375-180FB1CE-44BF-439E-9FE1-B5E3ABF4CC6C

Q34069375-2B080D3D-3579-4CDE-9384-32F46C7DCDCD

Q34069375-4E173D96-60C0-4FA5-9B1D-7242014183F8

Q34069375-77A68020-8CD4-4CB1-ADA2-1D81717CECC8

Q34069375-8DBA4A7B-C6B6-4D90-AA05-67B14A167672

Q34069375-AC90FE53-3059-4EF1-8CF6-51CCB631A176

P2860

Q34069375-008BE615-782C-4023-BC1B-88F20D11AD7B

Q34069375-01222498-9F2D-44DB-B5C6-4126BFB0E28D

Q34069375-0215893D-8BFB-4767-B4BE-7E2BAF45F675

Q34069375-06A4680E-25F6-4569-8E38-473845809FF1

Q34069375-0AC74070-4AA4-4E0D-8C18-A874E6BB9F3A

Q34069375-0D5401CB-4883-4AB0-90ED-6C4AA30AB7C3

Q34069375-10948A38-AC1D-4B0E-8F88-AB8C74DB7EC6

Q34069375-11D2CD45-505D-41F5-AEFA-A7EEE29806EC

Q34069375-1774A9BD-046B-40FB-BF44-ED8C597AEDB1

Q34069375-1F970955-8C73-4CF9-9587-2842F82B2587

P304

Q34069375-3B1308EC-19DA-4CDC-BB35-7B2B6E35D5D4

P31

Q34069375-4E8429E4-F6F6-4299-8413-FC06241454E5

P356

Q34069375-08E268DB-DD58-4D9B-98A4-37D476A0252D

P433

Q34069375-8C678BCA-659C-4E0A-A29D-348D4D6A4C96

P478

Q34069375-1DF800A0-AF9D-4599-9C97-8F2E19D0CB44

P50

Q34069375-0D101B4B-45D7-4288-847D-EA850EA581E6

Q34069375-D1E9B97D-7C75-49BE-8931-97E34EB6491D

Q34069375-FCC1278F-0941-4D63-9C36-FBD1030314F0

P577

Q34069375-17737418-28DC-4A13-B501-D4C11DE0E591

P5875

Q34069375-0B6506A1-1AD5-4F74-A962-F97417F1C174

P698

Q34069375-FCD5621E-BD65-4EF1-A94D-CC220B020827

P932

Q34069375-DC74269D-50EC-4E22-96DF-2ACE16F5AD10

P356

P1433

Genes & Development

P1476

Tumor heterogeneity is an acti ...... okine circuit in glioblastoma.

@en

P2093

Akitake Mukasa

http://www.w3.org/2001/XMLSchema#string

Dinah W Y Sah

http://www.w3.org/2001/XMLSchema#string

Maria-del-Mar Inda

http://www.w3.org/2001/XMLSchema#string

Pamela Tan

http://www.w3.org/2001/XMLSchema#string

Philipp Hadwiger

http://www.w3.org/2001/XMLSchema#string

Robert Bachoo

http://www.w3.org/2001/XMLSchema#string

Ronald A Depinho

http://www.w3.org/2001/XMLSchema#string

Rudy Bonavia

http://www.w3.org/2001/XMLSchema#string

Scott Vandenberg

http://www.w3.org/2001/XMLSchema#string

Webster Cavenee

http://www.w3.org/2001/XMLSchema#string

P2860

Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme.

Malignant astrocytic glioma: genetics, biology, and paths to treatment

Molecular characterization of the tumor microenvironment in breast cancer.

Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth

The WHO classification of tumors of the nervous system.

Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence.

Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission.

P304

1731-1745

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1101/GAD.1890510

http://www.w3.org/2001/XMLSchema#string

P433

16

http://www.w3.org/2001/XMLSchema#string

P478

24

http://www.w3.org/2001/XMLSchema#string

P50

Cameron Brennan

Frank B Furnari

Terrance G Johns

P577

2010-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

45659831

http://www.w3.org/2001/XMLSchema#string

P698

20713517

http://www.w3.org/2001/XMLSchema#string

P932

2922502

http://www.w3.org/2001/XMLSchema#string