PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis. - Wikidata - wikimedia - TriplyDB

PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis.

PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis.

http://www.wikidata.org/entity/Q40070753

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Chimeric RNAs generated by intergenic splicing in normal and cancer cells.Structural and functional studies of FKHR-PAX3, a reciprocal fusion gene of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth.Histone methyltransferase KMT1A restrains entry of alveolar rhabdomyosarcoma cells into a myogenic differentiated state The PAX3-FOXO1 fusion protein present in rhabdomyosarcoma interferes with normal FOXO activity and the TGF-β pathway.MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line.AKT and PAX3-FKHR cooperation enforces myogenic differentiation blockade in alveolar rhabdomyosarcoma cell MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state.Diagnostic and prognostic sarcoma signatures.PAX3 across the spectrum: from melanoblast to melanoma.Phosphorylation of serine 205 by the protein kinase CK2 persists on Pax3-FOXO1, but not Pax3, throughout early myogenic differentiation.Molecular and cellular biology of rhabdomyosarcoma.Marking the tempo for myogenesis: Pax7 and the regulation of muscle stem cell fate decisions Caveolins in rhabdomyosarcoma Rhabdomyosarcomas: an overview on the experimental animal models.Myogenic tumors in children and adolescents.Identification of target genes of PAX3-FOXO1 in alveolar rhabdomyosarcoma.Uncovering metabolism in rhabdomyosarcoma.Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma.PAX3-NCOA2 fusion gene has a dual role in promoting the proliferation and inhibiting the myogenic differentiation of rhabdomyosarcoma cells.Alternate PAX3 and PAX7 C-terminal isoforms in myogenic differentiation and sarcomagenesis.Pax7-FKHR transcriptional activity is enhanced by transcriptionally repressed MyoD.New approaches for pediatric rhabdomyosarcoma drug discovery: targeting combinatorial signaling.

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P2860

PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis.

http://www.wikidata.org/entity/Q40070753

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh

2007年學術文章

@zh-hant

name

PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis.

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type

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PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis.

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prefLabel

PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis.

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PAX-FKHR function as pangenes by simultaneously inducing and inhibiting myogenesis.

@en

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F Graf Finckenstein

http://www.w3.org/2001/XMLSchema#string

M J Anderson

http://www.w3.org/2001/XMLSchema#string

V Shahbazian

http://www.w3.org/2001/XMLSchema#string

Y-X Ren

http://www.w3.org/2001/XMLSchema#string

P2860

Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

Pax3 functions at a nodal point in melanocyte stem cell differentiation

Expression of a single transfected cDNA converts fibroblasts to myoblasts

Regulation of muscle regulatory factors by DNA-binding, interacting proteins, and post-transcriptional modifications.

Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3

FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains.

Pax3 inhibits myogenic differentiation of cultured myoblast cells.

PAX3-FKHR induces morphological change and enhances cellular proliferation and invasion in rhabdomyosarcoma

Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma.

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2004-2014

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scholarly article

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10.1038/SJ.ONC.1210835

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14

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27

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1036034976

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17922034

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