Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies.
about
Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic DiseasesTherapeutic targeting of redox signaling in myofibroblast differentiation and age-related fibrotic diseaseTGF-β signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunitiesPivotal role for decorin in angiogenesisSustained induction of collagen synthesis by TGF-β requires regulated intramembrane proteolysis of CREB3L1Transport mechanisms and their pathology-induced regulation govern tyrosine kinase inhibitor delivery in rheumatoid arthritisGraptopetalum paraguayense ameliorates chemical-induced rat hepatic fibrosis in vivo and inactivates stellate cells and Kupffer cells in vitroRepurposed drug screen identifies cardiac glycosides as inhibitors of TGF-β-induced cancer-associated fibroblast differentiationmiR-21 and miR-214 are consistently modulated during renal injury in rodent modelsNovel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinomaA synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responsesProteomic analysis identification of a pattern of shared alterations in the secretome of dermal fibroblasts from systemic sclerosis and nephrogenic systemic fibrosis.Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1.The effects of indoxyl sulfate-induced endothelial microparticles on neointimal hyperplasia formation in an ex vivo modelAltered MCM protein levels and autophagic flux in aged and systemic sclerosis dermal fibroblastsEgr-1 induces a profibrotic injury/repair gene program associated with systemic sclerosis.Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expressionComprehensive microRNA analysis in bleomycin-induced pulmonary fibrosis identifies multiple sites of molecular regulation.miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1Differential regulation of extracellular matrix and soluble fibulin-1 levels by TGF-β₁ in airway smooth muscle cellsImatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trialMyofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease.Cross-talk between miR-29 and transforming growth factor-betas in trabecular meshwork cells.TGFβ- and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR)The essential autophagy gene ATG7 modulates organ fibrosis via regulation of endothelial-to-mesenchymal transition.Protein kinase Cδ and c-Abl kinase are required for transforming growth factor β induction of endothelial-mesenchymal transition in vitroRole of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disordersFibronectinEDA promotes chronic cutaneous fibrosis through Toll-like receptor signaling.Imatinib ameliorates renal morphological changes in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertensionA phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis.Glucagon-Like Peptide 1 Protects against Hyperglycemic-Induced Endothelial-to-Mesenchymal Transition and Improves Myocardial Dysfunction by Suppressing Poly(ADP-Ribose) Polymerase 1 Activity.Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophagesThe Tumor Necrosis Factor Superfamily Molecule LIGHT Promotes Keratinocyte Activity and Skin Fibrosis.Tumor necrosis factor superfamily 14 (LIGHT) controls thymic stromal lymphopoietin to drive pulmonary fibrosis.Selective inhibition of prolyl 4-hydroxylases by bipyridinedicarboxylates.Effect of dietary salt on regulation of TGF-β in the kidney.CD109, a TGF-β co-receptor, attenuates extracellular matrix production in scleroderma skin fibroblasts.The adipokine adiponectin has potent anti-fibrotic effects mediated via adenosine monophosphate-activated protein kinase: novel target for fibrosis therapy.Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human CellsA vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response.
P2860
Q26748338-11926A41-34C0-4DDB-AC20-6E1A79CED49CQ26827629-0C2E9B34-BACA-4737-A0F3-C221DCD93CB4Q27022062-9E7B865F-2F7E-493B-8CB5-D46D65A2FB11Q28085303-A14A7EFD-71D4-4B3C-BA62-52A343254A95Q28117988-2A40C4D0-5419-4921-A37A-B59596F3FF7EQ28484465-7BD5A355-5FE1-4481-855B-3A3BA2730418Q28485116-087A7477-0061-4409-A43C-54928C6BA740Q28821190-1BCDA872-436B-4226-B5AF-E61D68B53EA4Q28854274-C266C65E-B5D2-4AD7-B8A7-84DB22EE29CDQ30360377-64A4269F-A989-41D7-B09F-6A8054285556Q33637862-D7349133-9237-4480-B3AC-D6F14244AF9BQ33665990-59F7104D-BD2F-4E0D-B5CD-884A3A29EE07Q33770085-70FB1620-F3F1-4783-845A-09E6FC5B407BQ33899084-A241E424-0B06-42B8-9E45-DA9758E0FBDAQ34000514-DA193D34-910D-48BD-8D63-B90854A10DC9Q34023076-E3FDCF92-0BD1-4DDF-A34C-090E865DAB53Q34031843-84A5E31D-CF8A-40AD-A209-094014ECA9E2Q34160776-29488ABE-238D-4045-85DE-EE462531A31BQ34607960-4E759456-81D0-412F-AF5D-13E409C9CB6AQ34770014-889C030D-CDAA-44AA-A9AA-D4034593C1E4Q34906164-ED7F5094-6502-4443-9B12-5BB95CB00DE2Q34946558-BFB706DC-7B38-4C73-8356-420039E4904BQ35027630-C3793A93-A91B-4289-A80F-DA7B35CA3674Q35041204-1E7B5C21-BCB3-4AD8-9F9C-9346BC66B7C5Q35048942-2DD53FE9-BD23-4A10-A830-99B55153007BQ35100214-0B1FEF44-AAD0-4635-B3B4-89E0C21FE4E0Q35168217-F21A40C6-B539-49E0-9DE9-8AF89A02AB53Q35551588-8E518BAC-7483-4492-B6CE-7C54E5F472A5Q35652125-C270C579-E63E-42C1-A430-A00AD4E6FB99Q35669295-A230BDC0-A2B3-43DB-8049-0F47EDF52D76Q35707164-79D6747B-C38F-4EE8-BF52-AEC079FA81F5Q35825861-16E1FA41-EC15-49CD-9BAA-C8D600408719Q35858686-2F4DF417-7621-4DBB-AF1A-DF12F7055EE9Q35941021-D515AC29-3260-487C-B762-94B61B90D674Q36004870-CE155DB1-E545-4ED6-AD14-12099F0A0A04Q36125220-36FC842B-CE16-4215-A67F-25E1CE5684AEQ36246124-CC9C63B9-4562-4AE2-9AB3-84E146D024E0Q36633255-0E721009-2093-46C6-A1AD-F9CBD6F319C2Q36703589-00DE2F38-EC86-46FA-9B3A-B6689845FE90Q36905046-16977498-CBE4-4F9F-AE29-9996634C6153
P2860
Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Narrative review: fibrotic dis ...... echanisms and novel therapies.
@ast
Narrative review: fibrotic dis ...... echanisms and novel therapies.
@en
Narrative review: fibrotic dis ...... echanisms and novel therapies.
@nl
type
label
Narrative review: fibrotic dis ...... echanisms and novel therapies.
@ast
Narrative review: fibrotic dis ...... echanisms and novel therapies.
@en
Narrative review: fibrotic dis ...... echanisms and novel therapies.
@nl
prefLabel
Narrative review: fibrotic dis ...... echanisms and novel therapies.
@ast
Narrative review: fibrotic dis ...... echanisms and novel therapies.
@en
Narrative review: fibrotic dis ...... echanisms and novel therapies.
@nl
P2093
P1476
Narrative review: fibrotic dis ...... echanisms and novel therapies.
@en
P2093
Joel Rosenbloom
Sergio A Jimenez
Susan V Castro
P304
P356
10.7326/0003-4819-152-3-201002020-00007
P407
P577
2010-02-01T00:00:00Z