Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association.
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Subdomain X of the kinase domain of Lck binds CD45 and facilitates dephosphorylationThe SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytesDistinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytesAssociation of immunoglobulin G Fc receptor II with Src-like protein-tyrosine kinase Fgr in neutrophilsDifferently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor proteinp70 phosphorylation and binding to p56lck is an early event in interleukin-2-induced onset of cell cycle progression in T-lymphocytesMolecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytesHuman homologue of the Drosophila discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytesHuman immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activityLck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cellsThe human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activityInterleukin 2 regulates the activity of the lyn protein-tyrosine kinase in a B-cell linep21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating proteinActivation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signalingDifferent interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferationCloning and characterization of R-PTP-kappa, a new member of the receptor protein tyrosine phosphatase family with a proteolytically cleaved cellular adhesion molecule-like extracellular regionThe T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p56lckFc epsilon R1-mediated tyrosine phosphorylation of multiple proteins, including phospholipase C gamma 1 and the receptor beta gamma 2 complex, in RBL-2H3 rat basophilic leukemia cellsAssociation between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinasesPathogenesis of human immunodeficiency virus infectionFunctional cleavage of the common cytokine receptor gamma chain (gammac) by calpainHierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activationInterleukin-6, CD45 and the src-kinases in myeloma cell proliferationFunction and molecular modeling of the interaction between human interleukin 6 and its HNK-1 oligosaccharide ligandsChoice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptorsInterleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cellsA novel human tyrosine kinase gene inducible in T cells by interleukin 2Association of 75/80-kDa phosphoproteins and the tyrosine kinases Lyn, Fyn, and Lck with the B cell molecule CD20. Evidence against involvement of the cytoplasmic regions of CD20The protein-tyrosine kinase Lck associates with and is phosphorylated by Cdc2Impaired development of V gamma 3 dendritic epidermal T cells in p56lck protein tyrosine kinase-deficient and CD45 protein tyrosine phosphatase-deficient miceEvidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signalingCD16-mediated p21ras activation is associated with Shc and p36 tyrosine phosphorylation and their binding with Grb2 in human natural killer cells.Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiriIdentification of Lck-binding elements in tip of herpesvirus saimiri.LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck.IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases.A novel nonreceptor tyrosine kinase, Srm: cloning and targeted disruption.The Src-family kinase, Fyn, regulates the activation of phosphatidylinositol 3-kinase in an interleukin 2-responsive T cell line.Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells.Hormone-conditional transformation by fusion proteins of c-Abl and its transforming variants
P2860
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P2860
Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association.
description
1991 nî lūn-bûn
@nan
1991 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Interaction of the IL-2 recept ...... el intermolecular association.
@ast
Interaction of the IL-2 recept ...... el intermolecular association.
@en
Interaction of the IL-2 recept ...... el intermolecular association.
@nl
type
label
Interaction of the IL-2 recept ...... el intermolecular association.
@ast
Interaction of the IL-2 recept ...... el intermolecular association.
@en
Interaction of the IL-2 recept ...... el intermolecular association.
@nl
prefLabel
Interaction of the IL-2 recept ...... el intermolecular association.
@ast
Interaction of the IL-2 recept ...... el intermolecular association.
@en
Interaction of the IL-2 recept ...... el intermolecular association.
@nl
P2093
P2860
P356
P1433
P1476
Interaction of the IL-2 recept ...... el intermolecular association.
@en
P2093
Hatakeyama M
Kawahara A
Kobayashi N
Perlmutter RM
Taniguchi T
P2860
P304
P356
10.1126/SCIENCE.2047859
P407
P577
1991-06-01T00:00:00Z