Interleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cells

Interleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cells

Item
http://www.wikidata.org/entity/Q28261435
The adaptor protein Crk in immune responseA yeast two-hybrid study of human p97/Gab2 interactions with its SH2 domain-containing binding partnersCrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signalingDAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinaseT cell activation induces direct binding of the Crk adapter protein to the regulatory subunit of phosphatidylinositol 3-kinase (p85) via a complex mechanism involving the Cbl protein.The adapter protein Crkl links Cbl to C3G after integrin ligation and enhances cell migration.CrkL mediates Ras-dependent activation of the Raf/ERK pathway through the guanine nucleotide exchange factor C3G in hematopoietic cells stimulated with erythropoietin or interleukin-3.T cell activation stimulates the association of enzymatically active tyrosine-phosphorylated ZAP-70 with the Crk adapter proteins.A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes.Roles of E3 ubiquitin ligases in cell adhesion and migration.Beyond the RING: CBL proteins as multivalent adapters.The interleukin (IL)-2 family cytokines: survival and proliferation signaling pathways in T lymphocytes.Biochemical analysis of interleukin-2 receptor beta chain phosphorylation by p56(lck).PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion.Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor.Growth hormone stimulates the formation of a multiprotein signaling complex involving p130(Cas) and CrkII. Resultant activation of c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK).
P2860

Interleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cells

Item
http://www.wikidata.org/entity/Q28261435
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Interleukin-2 stimulation indu ...... cytes and natural killer cells
@ast
Interleukin-2 stimulation indu ...... cytes and natural killer cells
@en
Interleukin-2 stimulation indu ...... cytes and natural killer cells
@nl
type
label
Interleukin-2 stimulation indu ...... cytes and natural killer cells
@ast
Interleukin-2 stimulation indu ...... cytes and natural killer cells
@en
Interleukin-2 stimulation indu ...... cytes and natural killer cells
@nl
prefLabel
Interleukin-2 stimulation indu ...... cytes and natural killer cells
@ast
Interleukin-2 stimulation indu ...... cytes and natural killer cells
@en
Interleukin-2 stimulation indu ...... cytes and natural killer cells
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Interleukin-2 stimulation indu ...... cytes and natural killer cells
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921