The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes
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Modulation of hepatic lipid metabolism by olive oil and its phenols in nonalcoholic fatty liver diseaseCurrent strategies to minimize hepatic ischemia-reperfusion injury by targeting reactive oxygen speciesOxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potentialAMPK Activation Prevents and Reverses Drug-Induced Mitochondrial and Hepatocyte Injury by Promoting Mitochondrial Fusion and FunctionMechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology.Oxygen tension modulates differentiation and primary macrophage functions in the human monocytic THP-1 cell lineHepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicityCurrent issues with acetaminophen hepatotoxicity--a clinically relevant model to test the efficacy of natural products.The role of hypoxia-inducible factor-1α in acetaminophen hepatotoxicity.Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity.Hepatitis C virus structural proteins can exacerbate or ameliorate acetaminophen-induced liver injury in mice.Critical Factors in the Assessment of Cholestatic Liver Injury In Vitro.Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products.Therapeutic targets for cholestatic liver injuryMetabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activationCyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury.Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicityQuantifying the magnitude of the oxygen artefact inherent in culturing airway cells under atmospheric oxygen versus physiological levels.Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signaling through mitochondria and NFE2L2/ARE pathwayHydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.Translocation of iron from lysosomes to mitochondria during acetaminophen-induced hepatocellular injury: Protection by starch-desferal and minocycline.Hepatoprotective action of celery (Apium graveolens) leaves in acetaminophen-fed freshwater fish (Pangasius sutchi).Acetaminophen Toxicity Novel Insights into Mechanisms and Future Perspectives.Effect of membranes on oxygen transfer rate and consumption within a newly developed three-compartment bioartificial liver device: Advanced experimental and theoretical studies.The importance of physiological oxygen concentrations in the sandwich cultures of rat hepatocytes on gas-permeable membranes.Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism.Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity.Mitochondrial-Lysosomal Axis in Acetaminophen Hepatotoxicity.
P2860
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P2860
The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The oxygen tension modulates a ...... injury in cultured hepatocytes
@ast
The oxygen tension modulates a ...... injury in cultured hepatocytes
@en
The oxygen tension modulates a ...... injury in cultured hepatocytes
@nl
type
label
The oxygen tension modulates a ...... injury in cultured hepatocytes
@ast
The oxygen tension modulates a ...... injury in cultured hepatocytes
@en
The oxygen tension modulates a ...... injury in cultured hepatocytes
@nl
prefLabel
The oxygen tension modulates a ...... injury in cultured hepatocytes
@ast
The oxygen tension modulates a ...... injury in cultured hepatocytes
@en
The oxygen tension modulates a ...... injury in cultured hepatocytes
@nl
P2093
P2860
P356
P1476
The oxygen tension modulates a ...... injury in cultured hepatocytes
@en
P2093
Anup Ramachandran
Hartmut Jaeschke
Hui-Min Yan
John J Lemasters
Mary Lynn Bajt
P2860
P304
P356
10.1093/TOXSCI/KFQ208
P577
2010-07-08T00:00:00Z