Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality. - Wikidata - wikimedia - TriplyDB

Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality.

Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality.

http://www.wikidata.org/entity/Q34148383

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Endothelial cell control of thrombosis Deficiency of superoxide dismutase impairs protein C activation and enhances susceptibility to experimental thrombosis Generation and phenotypic analysis of protein S-deficient mice.Enoxaparin use in pregnancy: state of the art.Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities.At Term, XmO and XpO Mouse Placentas Show Differences in Glucose Metabolism in the Trophectoderm-Derived Outer Zone Targeted gene sequencing identifies variants in the protein C and endothelial protein C receptor genes in patients with unprovoked venous thromboembolism.The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications An accompanying genetic severe deficiency of tissue factor protects mice with a protein C deficiency from lethal endotoxemia.Effects of membrane and soluble EPCR on the hemostatic balance and endotoxemia in mice Intraovarian thrombin and activated protein C signaling system regulates steroidogenesis during the periovulatory period.Extraembryonic expression of EPCR is essential for embryonic viability.The endothelial protein C receptor (PROCR) Ser219Gly variant and risk of common thrombotic disorders: a HuGE review and meta-analysis of evidence from observational studies.Fetomaternal cross talk in the placental vascular bed: control of coagulation by trophoblast cells.Relationship between Plasma D-Dimer Concentration and Three-Dimensional Ultrasound Placental Volume in Women at Risk for Placental Vascular Diseases: A Monocentric Prospective Study.Endothelial protein C receptor is overexpressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes Early rise in circulating endothelial protein C receptor correlates with poor outcome in severe sepsis PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells.A guide to murine coagulation factor structure, function, assays, and genetic alterations.Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin.Low levels of tissue factor rescue protein C-associated pregnancy failure in mice.Proteasome inhibitors enhance endothelial thrombomodulin expression via induction of Krüppel-like transcription factors.Endothelial Protein C Receptor gene Expression in a Female with Homozygous EPCR gene 23-bp Insertion The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling.Antithrombotic treatment for pregnancy complications: which path for the journey to precision medicine?Variations in the thrombomodulin and endothelial protein C receptor genes in couples with recurrent miscarriage.The Endothelial Protein C Receptor Is a Potential Stem Cell Marker for Epidermal Keratinocytes.Endothelial protein C receptor polymorphisms and risk of sepsis in a Chinese population.Fli1 deficiency contributes to the downregulation of endothelial protein C receptor in systemic sclerosis: a possible role in prothrombotic conditions.Single-cell RNA-seq reveals cell type-specific transcriptional signatures at the maternal-foetal interface during pregnancy.Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow Identification of multipotent mammary stem cells by protein C receptor expression.Circulating endothelial cell protein C receptor: endothelial regulation and cumulative impact of gender and A3 haplotype.Alternative mRNA is favored by the A3 haplotype of the EPCR gene PROCR and generates a novel soluble form of EPCR in plasma.Protective effects of transgenic human endothelial protein C receptor expression in murine models of transplantation.Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation.Bone up: craniomandibular development and hard-tissue biomineralization in neonate mice.WBSCR16 Is a Guanine Nucleotide Exchange Factor Important for Mitochondrial Fusion.Activation of Protein C in Human Trophoblasts in Culture and Downregulation of Trophoblast Endothelial Protein C Receptor by TNF-α.

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Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality.

http://www.wikidata.org/entity/Q34148383

description

2002 nî lūn-bûn

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2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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Disruption of the endothelial ...... and early embryonic lethality.

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Disruption of the endothelial ...... and early embryonic lethality.

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Disruption of the endothelial ...... and early embryonic lethality.

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Disruption of the endothelial ...... and early embryonic lethality.

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Disruption of the endothelial ...... and early embryonic lethality.

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Disruption of the endothelial ...... and early embryonic lethality.

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Disruption of the endothelial ...... and early embryonic lethality.

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Disruption of the endothelial ...... and early embryonic lethality.

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Disruption of the endothelial ...... and early embryonic lethality.

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Disruption of the endothelial ...... and early embryonic lethality

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Charles T Esmon

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Fangjiu Zhang

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Gary Ferrell

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Jian-Ming Gu

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Naomi L Esmon

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Weihong Li

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P2860

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice

The crystal structure of the endothelial protein C receptor and a bound phospholipid

Metalloproteolytic release of endothelial cell protein C receptor

Human protein C receptor is present primarily on endothelium of large blood vessels: implications for the control of the protein C pathway

Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR). The structural and functional conservation in human, bovine, and murine EPCR

Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system

The soluble endothelial protein C receptor binds to activated neutrophils: involvement of proteinase-3 and CD11b/CD18

Endothelial cell protein C receptor plays an important role in protein C activation in vivo

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

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45

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277

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