Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
about
Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearanceBile salts of vertebrates: structural variation and possible evolutionary significanceBile acids: regulation of synthesisThe Regulation of Steroid Action by Sulfation and DesulfationBile acid metabolism and signalingPeroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzymeAlterations of chemotherapeutic pharmacokinetic profiles by drug-drug interactionsAllopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's diseasePregnane X receptor and natural products: beyond drug-drug interactionsIntestinal detoxification limits the activation of hepatic pregnane X receptor by lithocholic acid.Minireview: Nuclear receptor-controlled steroid hormone synthesis and metabolismSulfotransferase genes: regulation by nuclear receptors in response to xeno/endo-biotics.On the general mechanism of selective induction of cytochrome P450 enzymes by chemicals: some theoretical considerations.The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species.Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells.Genetic and epigenetic regulation and expression signatures of glutathione S-transferases in developing mouse liver.Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Transcriptional regulation of human hydroxysteroid sulfotransferase SULT2A1 by LXRα.The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.Regulation of the human hydroxysteroid sulfotransferase (SULT2A1) by RORα and RORγ and its potential relevance to human liver diseases.Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.Pregnane X receptor as a therapeutic target to inhibit androgen activity.Cytochrome P450 and xenobiotic receptor humanized mice.Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CARAge- and sex-dependent expression of multiple murine hepatic hydroxysteroid sulfotransferase (SULT2A) genesBenefit of farnesoid X receptor inhibition in obstructive cholestasis.Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of pxr, CYP2, and CYP3 genes in developing zebrafish.Post-translational modification of pregnane x receptor.Targeting the pregnane X receptor in liver injury.Drug-activated nuclear receptors CAR and PXR.α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymesTranscriptional Regulation of CYP3A4/2B6/2C9 Mediated via Nuclear Receptor PXR by Helicid and Its MetabolitesXenobiotic- and vitamin D-responsive induction of the steroid/bile acid-sulfotransferase Sult2A1 in young and old mice: the role of a gene enhancer in the liver chromatin.Human constitutive androstane receptor mediated methotrexate induction of human dehydroepiandrosterone sulfotransferase (hSULT2A1).Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.The enterohepatic nuclear receptors are major regulators of the enterohepatic circulation of bile salts.Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXRInteraction of gut microbiota with bile acid metabolism and its influence on disease states.Top Three Pharmacogenomics and Personalized Medicine Applications at the Nexus of Renal Pathophysiology and Cardiovascular Medicine.
P2860
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P2860
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
@ast
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
@en
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor
@nl
type
label
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
@ast
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
@en
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor
@nl
prefLabel
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
@ast
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
@en
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor
@nl
P2093
P2860
P356
P1476
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
@en
P2093
John M Rosenfeld
Joyce L Barwick
Junichiro Sonoda
Philip S Guzelian
P2860
P304
13801-13806
P356
10.1073/PNAS.212494599
P407
P577
2002-10-07T00:00:00Z