Identification of a functional link for the p53 tumor suppressor protein in dexamethasone-induced growth suppression.
about
Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5Targeting protein serine/threonine phosphatases for drug developmentChaperoning steroidal physiology: lessons from mouse genetic models of Hsp90 and its cochaperonesAnxiety and the aging brain: stressed out over p53?The promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factorsSuppression of Ser/Thr phosphatase 4 (PP4C/PPP4C) mimics a novel post-mitotic action of fostriecin, producing mitotic slippage followed by tetraploid cell deathHigh yield expression of serine/threonine protein phosphatase type 5, and a fluorescent assay suitable for use in the detection of catalytic inhibitors.Regulation of apoptosis signal-regulating kinase 1 (ASK1) by polyamine levels via protein phosphatase 5.Glucocorticoid receptor and sequential P53 activation by dexamethasone mediates apoptosis and cell cycle arrest of osteoblastic MC3T3-E1 cells.Cantharidin-induced mitotic arrest is associated with the formation of aberrant mitotic spindles and lagging chromosomes resulting, in part, from the suppression of PP2AalphaPosttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5.Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor.Development and validation of a robust and sensitive assay for the discovery of selective inhibitors for serine/threonine protein phosphatases PP1α (PPP1C) and PP5 (PPP5C).Knockdown of protein phosphatase 5 inhibits ovarian cancer growth in vitro.The role of serine/threonine protein phosphatase type 5 (PP5) in the regulation of stress-induced signaling networks and cancerElevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancerThe glucocorticoid receptor signalling in breast cancer.Estrogen inhibits glucocorticoid action via protein phosphatase 5 (PP5)-mediated glucocorticoid receptor dephosphorylation.The phosphoprotein phosphatase family of Ser/Thr phosphatases as principal targets of naturally occurring toxins.Glucocorticoid receptor and breast cancer.Therapeutic strategies for head and neck cancer based on p53 status.Serine/Threonine Protein Phosphatase-5 Accelerates Cell Growth and Migration in Human Glioma.Inhibition of protein phosphatase 5 (PP5) suppresses survival and growth of colorectal cancer cells.L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells.P53 dependent mitochondrial permeability transition pore opening is required for dexamethasone-induced death of osteoblasts.MDM2 antagonist nutlin-3 is a potent inducer of apoptosis in pediatric acute lymphoblastic leukemia cells with wild-type p53 and overexpression of MDM2.Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole.Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade.Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.Structural basis for the catalytic activity of human serine/threonine protein phosphatase-5.Knockdown of PPP5C inhibits growth of hepatocellular carcinoma cells in vitro.The role of p53 in myelodysplastic syndromes and acute myeloid leukemia: molecular aspects and clinical implications.An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C)
P2860
Q24294415-32A06296-1FC1-4FDE-A6B6-6BD1160011B3Q24658001-606F3AEF-CBA2-41F6-8B9B-C0FC81059168Q27011776-8976088D-01F9-4778-9408-1D4A431229D9Q30433930-F71BA82A-4376-412A-9AF0-50390F00B471Q30436067-F61B5A75-7B77-4C3E-9322-0ECCD8EBE86AQ30543238-C78DD469-94AD-45F0-B7CD-0FEBD7CD6A62Q33302853-9C11FE33-8E9F-4818-8463-1F06D179EEC5Q34225710-0FD86B27-16D2-4E93-8507-DE1DFE04B06DQ34311717-79D7355F-76D7-4D76-A11C-96A3D30AEE22Q34667965-3D95592D-86FA-49D5-9742-8A96DA60002AQ34772282-9D187101-F7CF-4681-9CF8-BED906428E0BQ35345114-321CBA71-E66A-4772-BBB1-0F6EC5127718Q35406908-4ED447F6-E811-4C6C-A2AA-1074D767B37AQ36503266-0407B5B3-F3FB-4879-8A78-37BF20447E4AQ36804492-6FB2219C-4E24-4598-83F5-9D6B1BE52B5AQ36826622-EEEF6245-8165-4B88-BD33-962F28FD548BQ37021452-36F75371-9E3A-4B73-8CCA-3825CEE9C41DQ37433415-BC35C00A-7C48-4AB9-A6DB-926D7098AD67Q37834642-C38897A4-A666-42F0-A1D7-1914FA79FFD9Q37912048-B40543C3-E68A-4CBB-B829-694411A633DAQ38042630-8C9A5A60-E8B6-4A83-A84B-1672F23C366AQ38896812-E3794E45-7B66-49CD-A6E2-84929A040DA1Q38947186-C63C192F-FB21-4966-9B63-4B9A10C1298DQ38962094-DEE9AA06-E63F-4054-8DD1-69CA2FE76BB0Q39016683-CB06ECE8-B6A0-49E7-A24A-ADEC78F84EF7Q40013409-260E338F-79D8-4301-95EF-F8AE55CFB223Q40512925-E32399AF-8C40-4F53-8890-AA9E5448C4D8Q40522523-68F91F07-01AA-4DED-8865-5B804C905B77Q40919534-9E2EE4AC-4E45-484D-A886-75844C013BEDQ44904765-682D5A4F-622F-40A0-9714-848413A52B4BQ51041606-0EB97899-8FE7-4F23-A671-68766741F4A4Q52777531-AAAB2667-93F0-45AE-9307-34720A66ACCFQ56788667-0BEE3011-A169-4A7E-94D6-4ED75EA609C9
P2860
Identification of a functional link for the p53 tumor suppressor protein in dexamethasone-induced growth suppression.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Identification of a functional ...... ne-induced growth suppression.
@ast
Identification of a functional ...... ne-induced growth suppression.
@en
Identification of a functional ...... ne-induced growth suppression.
@nl
type
label
Identification of a functional ...... ne-induced growth suppression.
@ast
Identification of a functional ...... ne-induced growth suppression.
@en
Identification of a functional ...... ne-induced growth suppression.
@nl
prefLabel
Identification of a functional ...... ne-induced growth suppression.
@ast
Identification of a functional ...... ne-induced growth suppression.
@en
Identification of a functional ...... ne-induced growth suppression.
@nl
P2093
P2860
P356
P1476
Identification of a functional ...... ne-induced growth suppression.
@en
P2093
Gudrun Urban
Ileana V Aragon
Lex Cowsert
Nicholas M Dean
Richard E Honkanen
Scott R Cooper
Teresa Golden
P2860
P304
P356
10.1074/JBC.M210993200
P407
P577
2003-01-07T00:00:00Z